Anorchia 3842923 225639834 2008-07-14T18:06:24Z NetRolller 3D 420584 "Chromosome constellation" doesn't sound like the proper scientific term - replaced with "karyotype". {{Infobox_Disease | Name = {{PAGENAME}} | Image = | Caption = | DiseasesDB = 29633 | ICD10 = {{ICD10|Q|55|0|q|50}} | ICD9 = {{ICD9|752.89}} | ICDO = | OMIM = 273250 | MedlinePlus = 001185 | eMedicineSubj = | eMedicineTopic = | MeshID = | }} '''Anorchia''' (or '''anorchism''') is a medical condition where both [[testes]] are absent at [[childbirth|birth]]. Within a few weeks of [[fertilization]], the [[embryo]] develops rudimentary [[sex organs]], which are crucial to the development of the [[reproductive system]]. In the human male, if these fail to develop within eight weeks, the baby will have [[female]] genitalia (see [[Swyer syndrome]]). If the testes are lost between eight and 10 weeks, the baby will have [[ambiguous genitalia]] when it is born. However, if the testes are lost after 14 weeks, the baby will have a normal male [[reproductive system]], other than the absence of testes. Individuals with this condition have a 46,XY karyotype. Signs include an empty [[scrotum]] and lack of [[secondary sex characteristics]]. [[Medical test|Tests]] include [[testosterone]] levels (low); [[follicle stimulating hormone]] and [[luteinizing hormone]] levels (elevated); X,Y karyotype; [[ultrasound]] or [[magnetic resonance imaging]] showing absent gonadal tissue; [[bone density]] (low); [[anti-Mullerian hormone]] levels (low); surgical exploration for evidence of male gonadal tissue. ==Treatment== Treatment includes [[androgen]] (male hormone) supplementation, testicular prosthetic implantation, and psychological support. ==Other names== Other names for anorchia include *''congenital anorchia'' *''vanishing testes syndrome'' *''vanishing testes'' *''empty scrotum'' *''testicular regression syndrome (TRS)'' ==See also== * [[Cryptorchidism]] * [[Monorchism]] ==References== * {{cite web | title=Anorchia | work=University of Maryland Medical Center | url=http://www.umm.edu/ency/article/001185.htm | accessdate=January 25 | accessyear=2006}} http://www.nlm.nih.gov/medlineplus {{Congenital malformations of genital organs and urinary system}} [[Category:Congenital disorders]] [[cs:Anorchismus]] [[de:Anorchie]] [[pl:Anorchizm]]