Anorchia
3842923
225639834
2008-07-14T18:06:24Z
NetRolller 3D
420584
"Chromosome constellation" doesn't sound like the proper scientific term - replaced with "karyotype".
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = |
Caption = |
DiseasesDB = 29633 |
ICD10 = {{ICD10|Q|55|0|q|50}} |
ICD9 = {{ICD9|752.89}} |
ICDO = |
OMIM = 273250 |
MedlinePlus = 001185 |
eMedicineSubj = |
eMedicineTopic = |
MeshID = |
}}
'''Anorchia''' (or '''anorchism''') is a medical condition where both [[testes]] are absent at [[childbirth|birth]]. Within a few weeks of [[fertilization]], the [[embryo]] develops rudimentary [[sex organs]], which are crucial to the development of the [[reproductive system]]. In the human male, if these fail to develop within eight weeks, the baby will have [[female]] genitalia (see [[Swyer syndrome]]). If the testes are lost between eight and 10 weeks, the baby will have [[ambiguous genitalia]] when it is born. However, if the testes are lost after 14 weeks, the baby will have a normal male [[reproductive system]], other than the absence of testes.
Individuals with this condition have a 46,XY karyotype.
Signs include an empty [[scrotum]] and lack of [[secondary sex characteristics]].
[[Medical test|Tests]] include [[testosterone]] levels (low); [[follicle stimulating hormone]] and [[luteinizing hormone]] levels (elevated); X,Y karyotype; [[ultrasound]] or [[magnetic resonance imaging]] showing absent gonadal tissue; [[bone density]] (low); [[anti-Mullerian hormone]] levels (low); surgical exploration for evidence of male gonadal tissue.
==Treatment==
Treatment includes [[androgen]] (male hormone) supplementation, testicular prosthetic implantation, and psychological support.
==Other names==
Other names for anorchia include
*''congenital anorchia''
*''vanishing testes syndrome''
*''vanishing testes''
*''empty scrotum''
*''testicular regression syndrome (TRS)''
==See also==
* [[Cryptorchidism]]
* [[Monorchism]]
==References==
* {{cite web | title=Anorchia | work=University of Maryland Medical Center | url=http://www.umm.edu/ency/article/001185.htm | accessdate=January 25 | accessyear=2006}}
http://www.nlm.nih.gov/medlineplus
{{Congenital malformations of genital organs and urinary system}}
[[Category:Congenital disorders]]
[[cs:Anorchismus]]
[[de:Anorchie]]
[[pl:Anorchizm]]