Arteriosclerosis 188288 221459224 2008-06-24T16:19:38Z Fragaria Vesca 7350083 blue links {{Infobox_Disease | Name = Arteriosclerosis | Image = | Caption = | DiseasesDB = 1039 | ICD10 = {{ICD10|I|70||i|70}} | ICD9 = {{ICD9|440.9}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D001161 | }} '''Arteriosclerosis''' refers to a hardening of medium and large [[arteries]]. The most common form of arteriosclerosis is [[atherosclerosis]]. ==Etymology== The following terms are similar, yet distinct, in both spelling and meaning, and can be easily confused: arteriosclerosis, arteriolosclerosis, and atherosclerosis. '''Arteriosclerosis''' is a general term describing any hardening (and loss of elasticity) of medium or large arteries (from the Greek '''Arterio''', meaning ''artery'', and '''sclerosis''', meaning ''hardening''), '''arteriolosclerosis''' is any hardening (and loss of elasticity) of [[arteriole]]s (small arteries), '''atherosclerosis''' is a hardening of an artery specifically due to an atheromatous plaque. Therefore, atherosclerosis is a form of arteriosclerosis. ==Types== * [[Atherosclerosis]] is the most common form of arteriosclerosis. In atherosclerosis, thickening of the intima with plaques that can contain lipid-laden macrophages ("[[foam cells]]"). The plaques contain free lipid (cholesterol, etc.) and are prone to calcification and ulceration. * [[Arteriosclerosis obliterans]] is typically seen in medium and large arteries of the lower extremity. Characterized by fibrosis of the intima and calcification of the media. The lumen of the vessel may be obliterated or markedly narrowed. * [[Medial calcific sclerosis]] ([[Monckeberg’s calcific sclerosis]]) is seen mostly in the elderly, commonly in arteries of the thyroid and uterus. Characterized by calcification of the internal elastic lamina but without thickening of the intima or narrowing of the vessel lumen. A similar form of an intramural calcification, presenting the picture of an early phase of arteriosclerosis, appears to be induced by a number of drugs that have an antiproliferative mechanism of action ([[Rainer Liedtke]] 2008). * [[Hyaline arteriolosclerosis]] refers to thickening of the walls of arterioles by the deposition of [[hyaline]] material. Often seen in kidney pathology. == External links == * [http://www.rkliedtke.de/Arterial_Vascular_Effects_us.html Arterial Vascular Effects of Non-steroidal Antiphlogistic Drugs - A Biochemical Model on an Intramural Induction of Arteriosclerosis], Rainer K Liedtke, MD {{Vascular diseases}} [[Category:Cardiovascular diseases]] [[Category:Angiology]] [[Category:Cardiology]] [[ca:Arteriosclerosi]] [[es:Arteriosclerosis]]