Australian bat lyssavirus
2185035
210623785
2008-05-06T18:33:08Z
12.110.26.28
link
{{Taxobox
<!-- Color parameter is not needed -- automatically assigned -->
| name = ''{{PAGENAME}}''
| virus_group = v
| ordo = ''[[Mononegavirales]]''
| familia = ''[[Rhabdoviridae]]''
| genus = ''[[Lyssavirus]]''
| species = '''''{{PAGENAME}}'''''
}}
:''"ABLV" redirects here. [[ABV (TV station)|ABLV]] is also the callsign of the Australian Broadcasting Corporation's TV station in Gippsland and the Latrobe Valley, Victoria.''
'''Australian bat lyssavirus (ABLV)''' (initially named pteropid lyssavirus PLV) is a [[zoonosis|zoonotic]] [[virus]] closely related to [[rabies]] virus. It was first identified in a 5-month old juvenile Black [[flying fox]] (''[[Pteropus alecto]]'') collected near Ballina in northern [[New South Wales]], [[Australia]] in 1996 during a national surveillance program for the recently identified [[Hendra virus]]. ABLV is the seventh member of the [[lyssavirus]] genus (which includes rabies virus) and the only one present in Australia.
ABLV is distributed throughout Australia in a variety of bat species which are believed to be the primary reservoir for the virus. Two strains of the virus exist, one occurring in insectivorous bats and the other in fruit bats.
ABLV has caused two human deaths. The first occurred in November 1996 when an animal carer was scratched by a yellow-bellied sheathtailed bat. Onset of a rabies-like illness occurred 4-5 weeks following the incident, with death twenty days later. ABLV was identified from brain tissue by [[polymerase chain reaction|PCR]] and [[immunohistochemistry]].
In August 1996, a woman in Queensland was bitten on the finger by a [[flying fox]] while attempting to remove it from a child it had landed on. Six months later, following heightened public attention from the first ABLV death, she consulted a GP regarding testing for the virus. Post exposure treatment was advised but declined. After a 27 month incubation a rabies-like illness developed. The condition worsened after hospital admission and she died 19 days after the onset of illness. This length of incubation is unusual with typical incubation periods for classical rabies of less than 90 days.
Rabies [[vaccine]] and [[immunoglobulin]] are effective in prophylactic and therapeutic protection from ABLV infection. Since the emergence of the virus, rabies vaccine is administered to individuals with a heightened risk of exposure and vaccine and immunoglobulin are provided for post exposure treatment.
ABLV is one of four zoonotic viruses discovered in Pteropid bats since 1994, the others being [[Hendra virus]], [[Nipah virus]] and [[Menangle virus]]. Of these, ABLV is the only virus known to be transmissible to humans directly from bats without an intermediate host.
==References==
*Samaratunga, H, Searle, JW, Hudson, N. (1998). Non-rabies Lyssavirus human encephalitis from fruit bats: Australian bat Lyssavirus (pteropid Lyssavirus) infection. ''Neuropathol Appl Neurobiol'' '''24(4)''', 331–335.
*Hanna, JN, Carney, IK, Smith, GA, Tannenburg, AEG, Deverill, JE, Botha, JA, Serafin, IL, Harrower, BJ, Fitzpatrick, PF, Searle, JW. (2000). Australian bat lyssavirus infection: a second human case, with a long incubation period. ''Medical Journal of Australia'' '''172''', 597–599.
*Fraser, G. C., Hooper, P. T., Lunt, R. A., Gould, A. R., Gleeson, L. J., Hyatt, A. D., Russell, G. M. & Kattenbelt, J. A. (1996). Encephalitis caused by a Lyssavirus in fruit bats in Australia. ''Emerging Infectious Diseases'' '''2''', 327–331.
==External links==
* [http://www.health.gov.au/internet/wcms/publishing.nsf/Content/cda-pubs-other-bat_lyssa.htm Australian Bat Lyssavirus information documents - Communicable Diseases Network Australia (CDNA)]
{{Viral diseases}}
[[Category:Health in Australia]]
[[Category:Mononegavirales]]
[[Category:Zoonoses]]