Bacillus coagulans 2154601 217484770 2008-06-06T06:41:21Z Knorrepoes 3398035 replacing text and removing duplicate text and unsourced statement {{Taxobox | color = lightgrey | name = ''Bacillus coagulans'' | image = Bacillus coagulans 01.jpg | image_width = 240px | image_caption = [[Gram stain]] of ''Bacillus coagulans'' colonies. | regnum = [[Bacterium|Bacteria]] | phylum = [[Firmicutes]] | classis = [[Bacilli]] | ordo = [[Bacillales]] | familia = [[Bacillaceae]] | genus = ''[[Bacillus]]'' | species = '''''B. coagulans''''' | binomial = ''Bacillus coagulans'' | binomial_authority = Hammer, 1915 }} '''''Bacillus coagulans''''' is a [[lactic acid]] forming bacterial species within the genus ''[[Bacillus]]''. The organism was first isolated and described in 1932 and was elaborated in the fifth edition of Bergey’s Manual of Determinative Bacteriology. It was initially considered to be a spore-forming ''[[Lactobacillus]]''. Since ''Bacillus coagulans'' exhibits characteristics typical of both genera ''Lactobacillus'' and ''Bacillus'', its taxonomic position between the families ''Lactobacillaceae'' and ''Bacillaceae'' was often debated. However, in the seventh edition of Bergey’s, it was finally transferred to the genus Bacillus. DNA-based technology was used in distinguishing between the two genera of bacteria which are morphologically similar and possess similar physiological and biochemical characteristics.<ref>[http://www.food-info.net/uk/ff/sporogenes.htm Lactobacillus sporogenes a probiotioc species ?<!-- Bot generated title -->]</ref><ref>http://www.bacterio.cict.fr/allnamesac.html Official list of bacterial names</ref> B. coagulans is a [[Gram-positive]], spore-forming, motile rod (0.9μm by 3.0μm to 5.0μm in size), [[aerobic]] to [[microaerophilic]] and as all other species in genus ''Bacillus'', forms [[endospore]]s, which are resistant to chemical and physical agents. It may appear [[Gram-negative]] when entering the stationary phase of growth. The temperature optimum for growth is 50 °C. '''[[IMVic Tests]]''' VP and MR (methyl-red) tests are positive. [[Citrate]] and [[Nitrate]] tests are negative. ''Bacillus coagulans'' has been approved for veterinary purposes as [[GRAS]] by the [[FDA]]'s Center for Veterinary Medicine, as well as by the EU and is listed by [[AAFCO]] for use as a direct fed microbial in livestock production. Its main use is thus is veterinary applications, especially as a [[probiotic]] in pigs and shrimp. There are some references to use of this bacterium in humans, especially in improving the vaginal flora.<ref>http://members.ift.org/NR/rdonlyres/A23617C8-7A64-46AA-9F3C-85CB7FC104FE/0/crfsfsv2n3p101110ms20020667.pdf Sporeformers as Human Probiotics: ''Bacillus'', ''Sporolactobacillus'', and ''Brevibacillus</ref><ref>Hong et al., 2005; SCAN</ref><ref>http://www.newcenturyhealthpublishers.com/probiotics_and_prebiotics/about/pdf/3-10.pdf</ref> On activation of spore formation in the acidic environment of the stomach, this organism can germinate and proliferate in the intestine. '''''Bacillus coagulans''''' is often marketed as '''''Lactobacillus sporogenes''''' or a 'sporeforming lactic acid bacterium' [[probiotic]] , but this is an outdated name due to taxonomic changes in 1939. Although Bacillus coagulans does produce L+ lactic acid, the bacterium used in these products is not a lactic acid bacterium, as Bacillus species do not belong to the [[lactic acid bacteria]]. By definition, lactic acid bacteria (''[[Lactobacillus]]'', ''[[Bifidobacterium]]'') do not form spores. Therefore, using the name ''''Lactobacillus sporogenes'''' is scientifically incorrect.<ref>[http://www.food-info.net/uk/ff/sporogenes.htm Lactobacillus sporogenes a probiotioc species ?<!-- Bot generated title -->]</ref> ==References== {{reflist}} ==External links== *[http://www.ecosistemavaginale.it/Lactobacillus%20sporogenes%20or%20Bacillus%20coagulans.doc ''Lactobacillus sporogenes'' or ''Bacillus coagulans'': misidentification or mislabelling? (DOC file)] *[http://aem.highwire.org/cgi/content/abstract/70/4/2161 Hong, H. A., Duc, L. H., Cutting, S. M., 2005. The use of bacterial spore formers as probiotics. FEMS Microbiology Reviews 29, 813-835.] {{bacteria-stub}} {{Dietary supplement}} [[Category:Bacillaceae]] [[Category:Bacteriology]] [[Category:Digestive system]] [[Category:Probiotics]] [[Category:Microbiology]] [[es:Bacillus coagulans]] [[pt:Bacillus coagulans]]