Basal plate (neural tube) 5308738 164383723 2007-10-13T23:19:17Z Arcadian 104523 {{Development of nervous system}} {{dablink|This article is about the structure in the developing [[nervous system]]. For other uses of the term, see [[Basal plate]].}} {{Infobox Embryology | Name = Basal plate | Latin = Lamina basalis, basal lamina | GraySubject = 184 | GrayPage = 735 | Image = Gray642.png | Caption = The basal plate (basal lamina) is separated from the [[alar plate]] (alar lamina) by the [[sulcus limitans]] (unlabeled). | Width = 200 | Image2 = | Caption2 = | System = [[Nervous system]] | CarnegieStage = | Precursor = [[Neural tube]] | GivesRiseTo = [[Lower motor neuron]]s, [[interneuron]]s | MeshName = | MeshNumber = | DorlandsPre = l_02 | DorlandsSuf = 12475910 | }} In the developing [[nervous system]], the '''basal plate''' is the region of the [[neural tube]] ventral to the [[sulcus limitans]]. It extends from the rostral [[mesencephalon]] to the end of the [[spinal cord]] and contains primarily motor [[neuron]]s, whereas neurons found in the [[alar plate]] are primarily associated with sensory functions. The cell types of the basal plate include [[lower motor neuron]]s and four types of [[interneuron]].<ref name="carlson">{{cite book | author=Bruce M. Carlson | title=Human Embryology and Developmental Biology | publisher=Mosby | location=Saint Louis, MO | year=2004 | edition=2nd edition | id=ISBN 0-323-03649-X}}</ref> Initially the left and right sides of the basal plate are continuous, but during [[neurulation]] they become separated by the [[floor plate]], a derivative of the [[notochord]]. Differentiation of neurons in the basal plate is under the influence of [[Sonic hedgehog]] released by ventralizing structures such as the notochord and floor plate<ref name="carlson"/>. ==References== <references/> ==Bibliography== * {{cite book | author=John A. Kiernan | title=Barr's the Human Nervous System: An Anatomical Viewpoint | publisher=Lippincott Williams & Wilkins | location=Hagerstwon, MD | year=2005 | edition=8th edition | id=ISBN 0-7817-5154-3}} ==External links== * [http://isc.temple.edu/neuroanatomy/lab/embryo_new/spcd/2/ Overview at temple.edu] * {{BrainInfo|ancil|451}} {{Development of nervous system}} [[Category:Nervous system]] [[Category:Embryology]]