Basal plate (neural tube)
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2007-10-13T23:19:17Z
Arcadian
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{{Development of nervous system}}
{{dablink|This article is about the structure in the developing [[nervous system]]. For other uses of the term, see [[Basal plate]].}}
{{Infobox Embryology |
Name = Basal plate |
Latin = Lamina basalis, basal lamina |
GraySubject = 184 |
GrayPage = 735 |
Image = Gray642.png |
Caption = The basal plate (basal lamina) is separated from the [[alar plate]] (alar lamina) by the [[sulcus limitans]] (unlabeled). |
Width = 200 |
Image2 = |
Caption2 = |
System = [[Nervous system]] |
CarnegieStage = |
Precursor = [[Neural tube]] |
GivesRiseTo = [[Lower motor neuron]]s, [[interneuron]]s |
MeshName = |
MeshNumber = |
DorlandsPre = l_02 |
DorlandsSuf = 12475910 |
}}
In the developing [[nervous system]], the '''basal plate''' is the region of the [[neural tube]] ventral to the [[sulcus limitans]]. It extends from the rostral [[mesencephalon]] to the end of the [[spinal cord]] and contains primarily motor [[neuron]]s, whereas neurons found in the [[alar plate]] are primarily associated with sensory functions. The cell types of the basal plate include [[lower motor neuron]]s and four types of [[interneuron]].<ref name="carlson">{{cite book | author=Bruce M. Carlson | title=Human Embryology and Developmental Biology | publisher=Mosby | location=Saint Louis, MO | year=2004 | edition=2nd edition | id=ISBN 0-323-03649-X}}</ref>
Initially the left and right sides of the basal plate are continuous, but during [[neurulation]] they become separated by the [[floor plate]], a derivative of the [[notochord]]. Differentiation of neurons in the basal plate is under the influence of [[Sonic hedgehog]] released by ventralizing structures such as the notochord and floor plate<ref name="carlson"/>.
==References==
<references/>
==Bibliography==
* {{cite book | author=John A. Kiernan | title=Barr's the Human Nervous System: An Anatomical Viewpoint | publisher=Lippincott Williams & Wilkins | location=Hagerstwon, MD | year=2005 | edition=8th edition | id=ISBN 0-7817-5154-3}}
==External links==
* [http://isc.temple.edu/neuroanatomy/lab/embryo_new/spcd/2/ Overview at temple.edu]
* {{BrainInfo|ancil|451}}
{{Development of nervous system}}
[[Category:Nervous system]]
[[Category:Embryology]]