Bentiromide
5280980
225378194
2008-07-13T10:51:46Z
JaGa
2092487
add SVG image, ref
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| ImageFile=Bentiromide.svg
| ImageSize=150px
| IUPACName=<small>4-[2-benzamido-3- (4-hydroxyphenyl)- propanoyl] aminobenzoic acid</small>
| OtherNames=<small>(S)-4-((2-(benzoylamino)-3-(4-hydroxyphenyl) -1-oxopropyl)amino)benzoic acid<br />(S)-p-(α-benzamido-p-hydroxyhydrocinnamamido) benzoic acid<br />BRN 2910938<br />Benzoyltyrosyl-p-aminobenzoic acid (Btpaba)<br />C12779<br />CHEMBANK2959<br />Chymex<br />D01346<br />N-benzoyl-L-tyrosyl-p-aminobenzoic acid<br />P-((N-benzoyl-L-tyrosin)amido)benzoic acid<br />PFD<br />PFT<br />Ro 11-7891</small>
| Reference=<ref>[http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2329&loc=ec_rcs Bentiromide - Compound Summary], [[PubChem]].</ref>
| Section1={{Chembox Identifiers
| EINECS=253-349-8
| PubChem=2329
| Abbreviations=Btpaba
| CASNo=37106-97-1
| SMILES={{SMILES|S=C1=CC=C(C=C1)C(=O)NC(CC2=CC=C(C=C2)O) C(=O)NC3=CC=C(C=C3)C(=O)O}}
| InChI=1/C23H20N2O5/c26-19-12-6-15(7-13-19)14-20 (25-21(27)16-4-2-1-3-5-16)22(28)24-18-10-8-17 (9-11-18)23(29)30/h1-13,20,26H,14H2,(H,24,28) (H,25,27)(H,29,30)/f/h24-25,29H}}
| Section2={{Chembox Properties
| Formula=C<sub>23</sub>H<sub>20</sub>N<sub>2</sub>O<sub>5</sub>
| MolarMass=404.4153
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| Section5={{Chembox Pharmacology
| ATCCode=V04CK03
| DrugBank=APRD00818
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'''Bentiromide''' is a [[peptide]] used as a screening test for [[exocrine]] [[pancreatic]] insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is given by mouth as a noninvasive test. The amount of [[p-aminobenzoic acid|4-aminobenzoic acid]] and its [[metabolites]] excreted in the urine is taken as a measure of the [[chymotrypsin]]-secreting activity of the pancreas. Headache and gastrointestinal disturbances have been reported in patients taking bentiromide. Bentiromide is not available in the [[U.S.]] or [[Canada]] (It was withdrawn in the US in October 1996.)
==Data==
*XLogP=3.201
*tautomers=12
*H_bond_donor=4
*H_bond_acceptor=5
== See also ==
* [[chronic pancreatitis]]
* [[ATC_code_V04#V04CK_Tests_for_pancreatic_function]]
==References==
{{reflist}}
{{pharma-stub}}
[[Category:Benzoic acids]]