Benzamide 5586047 217336345 2008-06-05T16:15:17Z タチコマ robot 421426 robot Adding: [[pl:Benzamid]] {{Chembox new | ImageFile = Benzamide.png | ImageSize = | IUPACName = Benzamide | OtherNames = Benzoic acid amide, Phenyl carboxamide, Benzoylamide | Section1 = {{Chembox Identifiers | CASNo = 55-21-0 | EINECS = 200-227-7 | PubChem = 2331 | SMILES = C1=CC=C(C=C1)C(=O)N | InChI = 1/C7H7NO/c8-7(9)6-4-2-1- 3-5-6/h1-5H,(H2,8,9)/f/h8H2 | RTECS = CU8700000 }} | Section2 = {{Chembox Properties | Formula = C<sub>7</sub>H<sub>7</sub>NO | MolarMass = 121.14 g/mol | Appearance = Off-white solid | Density = 1.341 g/cm<sup>3</sup> | MeltingPt = 127 - 130 &deg;C | BoilingPt = 288 &deg;C | Solubility = 13 g/l pKa in DMSO = 23.35 }} | Section3 = {{Chembox Hazards | EUClass = Harmful ('''Xn''') | MainHazards = | FlashPt = 180 °C | Autoignition = > 500 °C | NFPA-H = 1 | NFPA-F = 1 | NFPA-R = 0 | NFPA-O = | RPhrases = {{R22}}, {{R40}} | SPhrases = {{S36/37/39}} }} }} '''Benzamide''' is an off-white solid with the chemical formula of C<sub>6</sub>H<sub>5</sub>CONH<sub>2</sub>. It is a derivative of [[benzoic acid]]. It is slightly soluble in water, and soluble in many organic solvents. ==Benzamides== [[Image:Amisulpride2d.svg|thumb|left|[[Amisulpride]] - a substituted benzamide]] Benzamides are a class of amides of benzoic acid. In [[psychiatry]] some substituted benzamides are therapeutically used as [[neuroleptics]] and/or [[antipsychotics]]. Two active substances from the group of benzamides are in use: * [[Sulpiride]] * [[Amisulpride]] Another benzamide, [[Remoxipride]], was taken off the market in 1993 because of life-threatening [[adverse drug reaction|side effects]]. Some [[analgetic]]s like [[salicylamide]] or [[ethenzamide]] also have benzamide structures. ==See also== * [[ATC code N05#N05AL Benzamides]] ==External links== * [http://www.chemicalland21.com/industrialchem/organic/BENZAMIDE.htm Physical characteristics] * [http://physchem.ox.ac.uk/MSDS/BE/benzamide.html Safety MSDS data] * {{GPnotebook|1309016066}} [[Category:Amines]] [[Category:Aromatic amines]] {{amine-stub}} [[de:Benzamide]] [[fr:Benzamide]] [[no:Benzamid]] [[pl:Benzamid]]