Berylliosis
195514
222137135
2008-06-27T19:02:13Z
158.111.4.26
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{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = Be-TableImage.svg |
Caption = [[Beryllium]] |
DiseasesDB = |
ICD10 = {{ICD10|J|63|2|j|60}} |
ICD9 = {{ICD9|503}} |
ICDO = |
OMIM = |
MedlinePlus = |
eMedicineSubj = med |
eMedicineTopic = 222 |
MeshID = |
}}
'''Berylliosis''' or '''chronic beryllium disease''' (CBD) is an [[occupational lung disease]]. It is a chronic allergic-type lung response and chronic lung [[disease]] caused by exposure to [[beryllium]] and its compounds. The condition is incurable but symptoms can be treated.
==Symptoms==
With single or prolonged exposure by inhalation, the lungs become hypersensitive to beryllium causing the development of small inflammatory nodules, called [[granulomas]].
Granulomas are seen in other chronic diseases, such as [[tuberculosis]], [[sarcoidosis]], and it can occasionally be hard to distinguish berylliosis from these disorders.
Ultimately, this process leads to restrictive lung disease, a decreased [[diffusion capacity]].
Clinically patients experience [[cough]] and [[shortness of breath]]. Other symptoms include [[chest pain]], [[joint aches]], [[weight loss]] and [[fever]].
Rarely, one can get granulomas in other organs including the [[liver]].
The onset of symptoms can range from weeks up to tens of years from the initial exposure. In some individuals a single exposure can cause berylliosis.
==External links==
* [http://www.atsdr.cdc.gov/csem/beryllium/ ATSDR Case Studies in Environmental Medicine: Beryllium Toxicity] U.S. [[Department of Health and Human Services]]
* [http://lungdiseases.about.com/od/berylliumlungdisease/ About.com]
* [http://respiratory-lung.health-cares.net/berylliosis.php Health-cares.net]
{{Respiratory pathology}}
[[Category:Pulmonology]]
[[Category:Element toxicology]]
[[Category:Beryllium]]
[[de:Berylliose]]
[[pl:Beryloza]]
[[ru:Бериллиоз]]