Bioinformatics Centre (Copenhagen University) 647581 190865582 2008-02-12T09:28:18Z Tomixdf 1645244 The '''Bioinformatics Center''' conducts interdisciplinary research in [[bioinformatics]] and is in charge of a masters program in bioinformatics. The center is affiliated with the Institute of Molecular Biology within the [[University of Copenhagen Faculty of Science|Faculty of Science]] of the [[University of Copenhagen]]. The center is headed by [[Anders Krogh]], who pioneered the use of [[hidden Markov models]] in [[bioinformatics]], together with [[David Haussler]]. The center further consists of six [[postdoc]]s and about 13 [[PhD]] students. There are four different subgroups in the center, each focussing on different topics: * Micro-RNA group: [[micro-RNA]]'s are small RNA molecules with important roles in regulation of [[gene expression]]. The group analyses the biology of micro-RNA's using computational methods and develop tools that are useful for experimental biologists. * Non-coding RNA group: Many RNA molecules play a functional role in the cell that is different from the classic role of serving as a template for [[protein synthesis]]. The group works on secondary structure prediction and multiple alignment of [[non-coding RNA]]'s. * Promotor analysis group: The group develops statistical and bioinformatics methods to analyze the regulation of [[transcription]] of [[eukaryote|eukaryotic]] [[gene]]s. This includes modelling of [[epigenetics]], [[transcription factor]] binding sites, core promoters and transcription start sites * Structure group: the group develops [[protein]] and [[RNA]] 3-D structure prediction methods based on [[graphical model]]s and [[Bayesian network]]s, [[directional statistics]] and [[Markov chain Monte Carlo]] methods. ==External links== *[http://www.binf.ku.dk Bioinformatics center website] [[Category:University of Copenhagen]] {{bioinformatics-stub}} {{sci-org-stub}} {{Denmark-stub}}