Bioinformatics Centre (Copenhagen University)
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190865582
2008-02-12T09:28:18Z
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The '''Bioinformatics Center''' conducts interdisciplinary research in [[bioinformatics]] and is in charge of a masters program in bioinformatics. The center is affiliated with the Institute of Molecular Biology within the [[University of Copenhagen Faculty of Science|Faculty of Science]] of the [[University of Copenhagen]].
The center is headed by [[Anders Krogh]], who pioneered the use of [[hidden Markov models]] in [[bioinformatics]], together with [[David Haussler]]. The center further consists of six [[postdoc]]s and about 13 [[PhD]] students.
There are four different subgroups in the center, each focussing on different topics:
* Micro-RNA group: [[micro-RNA]]'s are small RNA molecules with important roles in regulation of [[gene expression]]. The group analyses the biology of micro-RNA's using computational methods and develop tools that are useful for experimental biologists.
* Non-coding RNA group: Many RNA molecules play a functional role in the cell that is different from the classic role of serving as a template for [[protein synthesis]]. The group works on secondary structure prediction and multiple alignment of [[non-coding RNA]]'s.
* Promotor analysis group: The group develops statistical and bioinformatics methods to analyze the regulation of [[transcription]] of [[eukaryote|eukaryotic]] [[gene]]s. This includes modelling of [[epigenetics]], [[transcription factor]] binding sites, core promoters and transcription start sites
* Structure group: the group develops [[protein]] and [[RNA]] 3-D structure prediction methods based on [[graphical model]]s and [[Bayesian network]]s, [[directional statistics]] and [[Markov chain Monte Carlo]] methods.
==External links==
*[http://www.binf.ku.dk Bioinformatics center website]
[[Category:University of Copenhagen]]
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