Butalbital 2385806 215540825 2008-05-28T17:34:51Z Ohnoitsjamie 507787 rv spam {{drugbox | IUPAC_name = ''5-(2-methylpropyl)-5-(2-propenyl)-<BR>2,4,6(1''H'',3''H'',5''H'')-pyrimidinetrione'' | image = Butalbital.png | width = 160 | CAS_number = 77-26-9 | ATC_prefix = | ATC_suffix = | PubChem = 2481 | DrugBank = APRD00266 | C=11 | H=16 | N=2 | O=3 | molecular_weight = 224.256 | bioavailability = well absorbed | metabolism = [[Liver|hepatic]] | elimination_half-life = 35 hours | excretion = ? | pregnancy_US = D | pregnancy_category = | legal_US = Schedule III | routes_of_administration = oral }} '''Butalbital''', 5-allyl-5-isobutylbarbituric acid, is a [[barbiturate]] with an intermediate duration of action. It has the same chemical formula as [[talbutal]] but a different structure. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) or aspirin, and is commonly prescribed for the treatment of [[pain]] and [[headache]]. The various formulations combined with codeine are [[Food and Drug Administration|FDA]] approved for the treatment of [[tension headache]]s. Combinations include: *butalbital and [[paracetamol]] ([[acetaminophen]]) (trade names: Axocet, Bucet, Bupap, Cephadyn, Dolgic, Phrenilin, Phrenilin Forte, Sedapap) *butalbital, [[paracetamol]] (acetaminophen), and [[caffeine]] (trade names: [[Fioricet]], Esgic, Esgic-Plus) *butalbital and [[aspirin]] (trade name: Axotal) *butalbital, aspirin, and [[caffeine]] (trade names [[Fiorinal]], Fiormor, Fiortal, Fortabs, Laniroif) *butalbital, [[paracetamol]] ([[acetaminophen]]), [[caffeine]], and [[codeine phosphate]] ([[Fioricet #3 with Codeine]]) *butalbital, [[aspirin]], [[caffeine]], and [[codeine phosphate]] (trade name: [[Fiorinal #3 with Codeine]]) [[Image:Fioricet.jpg|thumb|right|60|Fioricet (50/40/325)]] ==Side effects== Side effects for any drug are difficult to predict, but commonly reported side effects for butalbital include: *[[Dizziness]] *[[Drowsiness]] *[[Intoxication|Intoxicated]] feeling *Light-headedness *[[Nausea]] *[[Sedation]] *[[Euphoria]] *[[Addiction]] *Severe impairment of [[judgement]] ''There are other potential side effects; this list should not be considered all-inclusive.'' ==Dangers and Risks== Butalbital is a [[Physical dependence|physically]] and psychologically addictive [[barbiturate]]. Butalbital should not be mixed with [[alcohol]] due to increased risk of intoxication, increased respiratory depression, and increased liver toxicity when it is a butalbital combination including paracetamol. ''There are other potential risks; this list should not be considered all-inclusive.'' ==External links== {{cite web | title=Butalbital | work=On-line Medical Dictionary | url=http://cancerweb.ncl.ac.uk/cgi-bin/omd?query=butalbital&action=Search+OMD | accessmonthday=June 26 | accessyear=2005}} {{cite web | title=Butalbital and Acetaminophen (Systemic) | work=MedicinePlus Drug Information | url=http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202102.html | accessmonthday=December 31 | accessyear=2006}} {{Cite web|url=http://www.deadiversion.usdoj.gov/schedules/listby_sched/sched3.htm|title=Controlled Substances in Schedule III|accessdate=2007-01-13|publisher=Drug Enforcement Administration|year=2007}} {{Barbiturates}} [[Category:Barbiturates]] [[Category:Sedatives]] [[fi:Butalbitaali]]