COX1 1740426 224259405 2008-07-08T01:13:18Z ProteinBoxBot 3991663 Replaced protein Box Template with PBB Template for easy viewing. {{Merge|Main subunit of cytochrome c oxidase|date=December 2007}} {{PBB|geneid=4512}} '''Cytochrome c oxidase subunit I''', also known as '''COX1''', is a human protein and [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: COX1 cytochrome c oxidase subunit I| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4512| accessdate = }}</ref> It belongs to [[cytochrome c oxidase subunit I]] protein family. <!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> {{PBB_Summary | section_title = | summary_text = }} ==References== {{reflist}} ==Further reading== {{refbegin | 2}} {{PBB_Further_reading | citations = *{{cite journal | author=Torroni A, Achilli A, Macaulay V, ''et al.'' |title=Harvesting the fruit of the human mtDNA tree |journal=Trends Genet. |volume=22 |issue= 6 |pages= 339–45 |year= 2006 |pmid= 16678300 |doi= 10.1016/j.tig.2006.04.001 }} *{{cite journal | author=Bodenteich A, Mitchell LG, Polymeropoulos MH, Merril CR |title=Dinucleotide repeat in the human mitochondrial D-loop |journal=Hum. Mol. Genet. |volume=1 |issue= 2 |pages= 140 |year= 1993 |pmid= 1301157 |doi= }} *{{cite journal | author=Brown MD, Yang CC, Trounce I, ''et al.'' |title=A mitochondrial DNA variant, identified in Leber hereditary optic neuropathy patients, which extends the amino acid sequence of cytochrome c oxidase subunit I |journal=Am. J. Hum. Genet. |volume=51 |issue= 2 |pages= 378–85 |year= 1992 |pmid= 1322638 |doi= }} *{{cite journal | author=Lu X, Walker T, MacManus JP, Seligy VL |title=Differentiation of HT-29 human colonic adenocarcinoma cells correlates with increased expression of mitochondrial RNA: effects of trehalose on cell growth and maturation |journal=Cancer Res. |volume=52 |issue= 13 |pages= 3718–25 |year= 1992 |pmid= 1377597 |doi= }} *{{cite journal | author=Marzuki S, Noer AS, Lertrit P, ''et al.'' |title=Normal variants of human mitochondrial DNA and translation products: the building of a reference data base |journal=Hum. Genet. |volume=88 |issue= 2 |pages= 139–45 |year= 1992 |pmid= 1757091 |doi= }} *{{cite journal | author=Moraes CT, Andreetta F, Bonilla E, ''et al.'' |title=Replication-competent human mitochondrial DNA lacking the heavy-strand promoter region |journal=Mol. Cell. Biol. |volume=11 |issue= 3 |pages= 1631–7 |year= 1991 |pmid= 1996112 |doi= }} *{{cite journal | author=Attardi G, Chomyn A, Doolittle RF, ''et al.'' |title=Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase |journal=Cold Spring Harb. Symp. Quant. Biol. |volume=51 Pt 1 |issue= |pages= 103–14 |year= 1987 |pmid= 3472707 |doi= }} *{{cite journal | author=Chomyn A, Cleeter MW, Ragan CI, ''et al.'' |title=URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit |journal=Science |volume=234 |issue= 4776 |pages= 614–8 |year= 1986 |pmid= 3764430 |doi=10.1126/science.3764430 }} *{{cite journal | author=Chomyn A, Mariottini P, Cleeter MW, ''et al.'' |title=Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase |journal=Nature |volume=314 |issue= 6012 |pages= 592–7 |year= 1985 |pmid= 3921850 |doi=10.1038/314592a0 }} *{{cite journal | author=Sanger F, Coulson AR, Barrell BG, ''et al.'' |title=Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing |journal=J. Mol. Biol. |volume=143 |issue= 2 |pages= 161–78 |year= 1981 |pmid= 6260957 |doi=10.1016/0022-2836(80)90196-5 }} *{{cite journal |author=Montoya J, Ojala D, Attardi G |title=Distinctive features of the 5'-terminal sequences of the human mitochondrial mRNAs |journal=Nature |volume=290 |issue= 5806 |pages= 465–70 |year= 1981 |pmid= 7219535 |doi=10.1038/290465a0 }} *{{cite journal | author=Horai S, Hayasaka K, Kondo R, ''et al.'' |title=Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 2 |pages= 532–6 |year= 1995 |pmid= 7530363 |doi=10.1073/pnas.92.2.532 }} *{{cite journal | author=Gattermann N, Retzlaff S, Wang YL, ''et al.'' |title=Heteroplasmic point mutations of mitochondrial DNA affecting subunit I of cytochrome c oxidase in two patients with acquired idiopathic sideroblastic anemia |journal=Blood |volume=90 |issue= 12 |pages= 4961–72 |year= 1997 |pmid= 9389715 |doi= }} *{{cite journal | author=Bröker S, Meunier B, Rich P, ''et al.'' |title=MtDNA mutations associated with sideroblastic anaemia cause a defect of mitochondrial cytochrome c oxidase |journal=Eur. J. Biochem. |volume=258 |issue= 1 |pages= 132–8 |year= 1998 |pmid= 9851701 |doi=10.1046/j.1432-1327.1998.2580132.x }} *{{cite journal | author=Andrews RM, Kubacka I, Chinnery PF, ''et al.'' |title=Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA |journal=Nat. Genet. |volume=23 |issue= 2 |pages= 147 |year= 1999 |pmid= 10508508 |doi= 10.1038/13779 }} *{{cite journal | author=Karadimas CL, Greenstein P, Sue CM, ''et al.'' |title=Recurrent myoglobinuria due to a nonsense mutation in the COX I gene of mitochondrial DNA |journal=Neurology |volume=55 |issue= 5 |pages= 644–9 |year= 2000 |pmid= 10980727 |doi= }} *{{cite journal | author=Ingman M, Kaessmann H, Pääbo S, Gyllensten U |title=Mitochondrial genome variation and the origin of modern humans |journal=Nature |volume=408 |issue= 6813 |pages= 708–13 |year= 2001 |pmid= 11130070 |doi= 10.1038/35047064 }} *{{cite journal | author=Finnilä S, Lehtonen MS, Majamaa K |title=Phylogenetic network for European mtDNA |journal=Am. J. Hum. Genet. |volume=68 |issue= 6 |pages= 1475–84 |year= 2001 |pmid= 11349229 |doi=10.1086/320591 }} *{{cite journal | author=Maca-Meyer N, González AM, Larruga JM, ''et al.'' |title=Major genomic mitochondrial lineages delineate early human expansions |journal=BMC Genet. |volume=2 |issue= |pages= 13 |year= 2003 |pmid= 11553319 |doi= }} }} {{refend}} {{protein-stub}} <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> {{PBB_Controls | update_page = yes | require_manual_inspection = no | update_protein_box = yes | update_summary = yes | update_citations = yes }}