California encephalitis virus
2939018
176098412
2007-12-06T05:40:50Z
G716
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update taxobox
{{Taxobox
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| name = ''{{PAGENAME}}''
| virus_group = v
| familia = ''[[Bunyaviridae]]''
| genus = ''[[Orthobunyavirus]]''
| species = '''''California encephalitis virus'''''
}}
'''California encephalitis virus''' causes [[encephalitis]] in humans. [[Mosquito]]s serve as its [[vector (biology)|vector]]s. For this reason this virus is known as an [[arbovirus]] (arthropod-borne virus).
California encephalitis virus belongs to the [[Bunyaviridae]] family of viruses, and the genus [[Bunyavirus]]. It was first discovered in [[1943]] in the California Central Valley region of the [[United States]] and is a rare cause of disease in the Western World.
Initial infection by the virus and primary viremia causes the onset of non-specific symptoms such as headache and fever. Secondary viremia and the multiplication of the virus in the CNS causes symptoms such as stiff neck, [[lethargy]] and [[seizures]]. It can also cause [[encephalitis]], when inflammation of the brain produced by infection of the virus damages nerve cells, which affects signalling of the brain to the body.
The virus particle is enveloped and contains three nucleocapsids. The envelope conatins G1 glycoproteins and neutralising [[antibodies]] against these proteins block fusion of the virus with host cells and inhibit [[haemagglutination]]. The virus gemone is over 12000 [[nucleotides]] in length and consists of three segments of various sized single-stranded [[RNA]] (negative sense and ambi-sense).
CEV is closely related to [[La_Crosse_encephalitis|La Crosse Virus]].
==References==
*http://medinfo.ufl.edu/year2/mmid/bms5300/bugs/cenceph.html
[[Category:Encephalitis]]
[[Category:Viruses]]
{{virus-stub}}
[[Category:Bunyaviruses]]