Carbamoyl phosphate
330893
224772446
2008-07-10T10:22:50Z
89.238.26.220
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| ImageFile = CarbPhos.png
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| Section1 = {{Chembox Identifiers
| CASNo = 590-55-6
| PubChem = 278
| SMILES = C(=O)(N)OP(=O)(O)O
| MeSHName = Carbamoyl+phosphate
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| Section2 = {{Chembox Properties
| Formula = CH<sub>4</sub>NO<sub>5</sub>P
| MolarMass = 141.020 g/mol
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| Section3 = {{Chembox Hazards
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'''Carbamoyl phosphate''' is an [[anion]] of biochemical significance. It is involved In ridding the body of excess [[nitrogen]] in the [[urea cycle]], and also in the synthesis of [[pyrimidine]]s.
It is produced from [[bicarbonate]], [[ammonia]], and [[phosphate]], the latter derived from [[Adenosine triphosphate|ATP]]. The synthesis is catalysed by the enzyme [[carbamoyl phosphate synthase]], as follows:
* HCO<sub>3</sub><sup>-</sup> + ATP --> ADP + HO-C(O)-OPO<sub>3</sub><sup>-2</sup> (carbonyl phosphate)
* HO-C(O)-OPO<sub>3</sub><sup>-2</sup> + NH<sub>3</sub> + OH<sup>-</sup> → HPO<sub>4</sub><sup>2-</sup> + [[Carbamate|<sup>-</sup>O-C(O)NH<sub>2</sub>]] + H<sub>2</sub>O
*<sup>-</sup>O-C(O)NH<sub>2</sub> + ATP → ADP + H<sub>2</sub>NC(O)OPO<sub>3</sub><sup>2-</sup>
==See also==
* [[Ornithine transcarbamylase]]
==References==
*{{cite book | author= Nelson, David L. and Michael M. Cox | title= Lehninger Principles of Biochemistry fourth edition | publisher=W. H. Freeman and company New York}}
{{Nucleotide metabolism intermediates}}
[[Category:Organophosphates]]
[[Category:Carbamates]]
[[ast:Carbamoil fosfatu]]
[[de:Carbamoylphosphat]]
[[ja:カルバモイルリン酸]]
[[pl:Karbamoilofosforan]]