Cathine
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2008-06-23T21:47:56Z
SpBot
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robot Removing: [[pl:Katyna]]
{{Refimprove|date=December 2007}}
{{drugbox |
| IUPAC_name = 2-amino-1-phenyl-propan-1-ol
| image = Pseudonorephedrine.png
| image2 = Cathine-3d-CPK.png
| CAS_number = 492-39-7
| ATC_prefix = A08
| ATC_suffix = AA07
| PubChem = 441457
| DrugBank =
| chemical_formula =
| C=9|H=13|N=1|O=1
| molecular_weight = 151.206
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category=
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C -->
| legal_US = Schedule IV <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status =
| routes_of_administration = Chewing ''Catha edulis'' leaves.
}}
{{dablink|For the alkaloid found in plants such as coffee and tea, see [[Caffeine]].}}
'''Cathine''' (D-[[Phenylpropanolamine|norpseudoephedrine]]) is a [[monoamine]] [[alkaloid]] found in the [[shrub]] ''[[Catha edulis]]'' (khat).
==Pharmacology==
Closely related to [[ephedrine]], [[cathinone]] and other [[amphetamines]], it may contribute to the [[stimulant]] effect of [[Khat|''Catha edulis'']], although another constituent, [[cathinone]] appears to show stronger activity. Cathine is one of the [[optical isomer]]s of [[phenylpropanolamine]], an [[appetite suppressant]] and [[decongestant]] which is possibly associated with an increased risk of hemorrhagic [[stroke]].
==Regulation==
The [[World Anti-Doping Agency]]'s list of prohibited substances (used for the [[Olympic Games]] among other athletic events) bars cathine in concentrations of over 5 [[microgram]]s per [[milliliter]] in [[urine]]. Cathine is a [[Schedule III]] drug under the [[Convention on Psychotropic Substances]].<ref>[http://www.incb.org/pdf/e/list/green.pdf List of pychotropic substances under international control] (pdf)</ref> In the United States, it is classified as a [[Schedule IV]] [[controlled substance]].
[[Image:Catha edulis.jpg|thumb|left|250px|Cathine is found in shrub ''[[Catha edulis]]''.]]
In [[Hong Kong]], cathine is regulated under Schedule 1 of [[Hong Kong|Hong Kong's]] Chapter 134 ''Dangerous Drugs Ordinance''. It can only be used legally by health professionals and for university research purposes. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000 (HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 ([[Hong Kong dollar|HKD]]) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a [[Hong Kong dollar|HK$]] 1,000,000 fine and/or 7 years of jail time.
==References==
<references/>
==See also==
* ''[[Catha edulis]]''
* [[Cathinone]]
* [[Methcathinone]]
* [[Phenylpropanolamine]]
* [[Phenethylamine]]s
{{Amphetamines}}
{{Antiobesity preparations}}
[[Category:Alcohols]]
[[Category:Amphetamine alkaloids]]
[[Category:Decongestants]]
[[Category:Stimulants]]
[[Category:Sympathomimetic amines]]
[[Category:DEA List I chemicals]]
{{drug-stub}}
[[da:Cathin]]
[[de:Cathin]]
[[fr:Cathine]]
[[sv:Katin]]