Cathine 609980 221290560 2008-06-23T21:47:56Z SpBot 7016748 robot Removing: [[pl:Katyna]] {{Refimprove|date=December 2007}} {{drugbox | | IUPAC_name = 2-amino-1-phenyl-propan-1-ol | image = Pseudonorephedrine.png | image2 = Cathine-3d-CPK.png | CAS_number = 492-39-7 | ATC_prefix = A08 | ATC_suffix = AA07 | PubChem = 441457 | DrugBank = | chemical_formula = | C=9|H=13|N=1|O=1 | molecular_weight = 151.206 | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_US = <!-- A / B / C / D / X --> | pregnancy_category= | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | legal_US = Schedule IV <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_status = | routes_of_administration = Chewing ''Catha edulis'' leaves. }} {{dablink|For the alkaloid found in plants such as coffee and tea, see [[Caffeine]].}} '''Cathine''' (D-[[Phenylpropanolamine|norpseudoephedrine]]) is a [[monoamine]] [[alkaloid]] found in the [[shrub]] ''[[Catha edulis]]'' (khat). ==Pharmacology== Closely related to [[ephedrine]], [[cathinone]] and other [[amphetamines]], it may contribute to the [[stimulant]] effect of [[Khat|''Catha edulis'']], although another constituent, [[cathinone]] appears to show stronger activity. Cathine is one of the [[optical isomer]]s of [[phenylpropanolamine]], an [[appetite suppressant]] and [[decongestant]] which is possibly associated with an increased risk of hemorrhagic [[stroke]]. ==Regulation== The [[World Anti-Doping Agency]]'s list of prohibited substances (used for the [[Olympic Games]] among other athletic events) bars cathine in concentrations of over 5 [[microgram]]s per [[milliliter]] in [[urine]]. Cathine is a [[Schedule III]] drug under the [[Convention on Psychotropic Substances]].<ref>[http://www.incb.org/pdf/e/list/green.pdf List of pychotropic substances under international control] (pdf)</ref> In the United States, it is classified as a [[Schedule IV]] [[controlled substance]]. [[Image:Catha edulis.jpg|thumb|left|250px|Cathine is found in shrub ''[[Catha edulis]]''.]] In [[Hong Kong]], cathine is regulated under Schedule 1 of [[Hong Kong|Hong Kong's]] Chapter 134 ''Dangerous Drugs Ordinance''. It can only be used legally by health professionals and for university research purposes. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000 (HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 ([[Hong Kong dollar|HKD]]) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a [[Hong Kong dollar|HK$]] 1,000,000 fine and/or 7 years of jail time. ==References== <references/> ==See also== * ''[[Catha edulis]]'' * [[Cathinone]] * [[Methcathinone]] * [[Phenylpropanolamine]] * [[Phenethylamine]]s {{Amphetamines}} {{Antiobesity preparations}} [[Category:Alcohols]] [[Category:Amphetamine alkaloids]] [[Category:Decongestants]] [[Category:Stimulants]] [[Category:Sympathomimetic amines]] [[Category:DEA List I chemicals]] {{drug-stub}} [[da:Cathin]] [[de:Cathin]] [[fr:Cathine]] [[sv:Katin]]