Chlortalidone
1128945
223478970
2008-07-04T06:57:28Z
Numbo3-bot
7118326
robot Adding: [[ja:クロルタリドン]]
{{drugbox
| IUPAC_name = 2-chloro-5-(1-hydroxy-3-oxo-1,2-dihydroisoindol-1-yl)- benzenesulfonamide
| image = Chlortalidone.svg
| CAS_number = 77-36-1
| ATC_prefix = C03
| ATC_suffix = BA04
| PubChem = 2732
| DrugBank = APRD00127
| C = 14 |H = 11 |Cl = 1 |N = 2 |O = 4 |S = 1
| molecular_weight = 338.767 [[Gram|g]]/[[Mole (unit)|mol]]
| bioavailability =
| protein_bound = 75%
| metabolism =
| elimination_half-life = 40 hours
| excretion = [[Kidney|Renal]]
| pregnancy_category = C <small>([[Australia|Au]])</small>, B <small>([[United States|U.S.]])</small>
| legal_status = [[Prescription drug|POM]] <small>([[United Kingdom|UK]])</small>
| routes_of_administration = Oral
}}
'''Chlortalidone''' (formerly spelled chlort<u>h</u>alidone in the UK, and still so called in the United States) is a drug used to treat hypertension. It is described as a [[thiazide diuretic]] (or, rather, a thiazide-like diuretic because it acts similarly to the thiazides but does not contain the [[benzothiadiazine]] molecular structure).
It is also available in the UK as a combination product with the [[beta blocker]] [[atenolol]] as [[Co-tenidone]].
{{pharma-stub}}
{{Antihypertensives and diuretics}}
[[Category:Thiazides]]
[[de:Chlortalidon]]
[[hr:Klortalidon]]
[[it:Clortalidone]]
[[ja:クロルタリドン]]
[[pl:Chlortalidon]]