Digitonin
2729712
190039022
2008-02-08T21:17:41Z
BobertWABC
5672942
/* Biological Properties */
[[Image:Digitonin.png|thumb|right|300px|Structure of Digitonin]]
'''Digitonin''' is a [[glycoside]] obtained from ''[[Digitalis purpurea]]''; the [[aglycone]] is [[digitogenin]]. Used as a detergent, it effectively water-solubilizes lipids. As such, it has several [[biological membrane|membrane]]-related applications in biochemistry, including solubilizing [[membrane protein]]s, precipitating [[cholesterol]], and permeabilizing cell membranes.
Digitonin is sometimes confused with the [[cardiac]] drug [[digoxin]] (sometimes also called digitalis or digitoxin), but has no heart-related effects.
==Physical & Chemical Properties==
'''Chemical Formula'''= C<sub>56</sub>H<sub>92</sub>O<sub>29</sub> <br>
'''Molecular Weight'''= 1229.3<br>
'''Appearance''' = White to off-white powder <br>
'''Boiling Point/Melting Point'''= 230 °C to 240 °C <br>
'''[[Specific Rotation]]'''= -47 TO -49º (10 g/100 ml 75%
Acetic Acid at 25 °C)1 <br>
'''[[wikt:aggregation number|Aggregation number]]''' = 60.
==Biological Properties==
'''Rat-LD<sub>50</sub>''' : 4 mg/kg body weight (IVN), 51 mg/kg body weight (ORAL)
==External links==
{{organic-compound-stub}}
{{Glycosides}}
[[Category:Glycosides]]
[[de:Digitonin]]
[[ja:ジギトニン]]