Digitonin 2729712 190039022 2008-02-08T21:17:41Z BobertWABC 5672942 /* Biological Properties */ [[Image:Digitonin.png|thumb|right|300px|Structure of Digitonin]] '''Digitonin''' is a [[glycoside]] obtained from ''[[Digitalis purpurea]]''; the [[aglycone]] is [[digitogenin]]. Used as a detergent, it effectively water-solubilizes lipids. As such, it has several [[biological membrane|membrane]]-related applications in biochemistry, including solubilizing [[membrane protein]]s, precipitating [[cholesterol]], and permeabilizing cell membranes. Digitonin is sometimes confused with the [[cardiac]] drug [[digoxin]] (sometimes also called digitalis or digitoxin), but has no heart-related effects. ==Physical & Chemical Properties== '''Chemical Formula'''= C<sub>56</sub>H<sub>92</sub>O<sub>29</sub> <br> '''Molecular Weight'''= 1229.3<br> '''Appearance''' = White to off-white powder <br> '''Boiling Point/Melting Point'''= 230 °C to 240 °C <br> '''[[Specific Rotation]]'''= -47 TO -49º (10 g/100 ml 75% Acetic Acid at 25 °C)1 <br> '''[[wikt:aggregation number|Aggregation number]]''' = 60. ==Biological Properties== '''Rat-LD<sub>50</sub>''' : 4 mg/kg body weight (IVN), 51 mg/kg body weight (ORAL) ==External links== {{organic-compound-stub}} {{Glycosides}} [[Category:Glycosides]] [[de:Digitonin]] [[ja:ジギトニン]]