Dressler's syndrome
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Name = {{PAGENAME}} |
ICD10 = {{ICD10|I|24|1|i|20}} |
ICD9 = {{ICD9|411.0}} |
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eMedicineSubj = |
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DiseasesDB = 3947 |
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'''Dressler's syndrome''' is a form of [[pericarditis]] that occurs in the setting of injury to the [[heart]] or the [[pericardium]] (the outer lining of the heart).
Dressler's syndrome is also known as '''postmyocardial infarction syndrome''' and '''postcardiotomy pericarditis'''.
==Presentation==
The syndrome consists of a persistent low-grade [[fever]], [[chest pain]] (usually [[pleuritic]] in nature), a [[pericardial friction rub]], and /or a [[pericardial effusion]]. The symptoms tend to occur after a few weeks or even months after infarction and tend to subside in a few days. An elevated [[Erythrocyte sedimentation rate|ESR]] is an objective laboratory finding.
==Causes==
It is believed to result from an [[autoimmune]] inflammatory reaction to myocardial neo-[[antigen]]s.
Dressler's syndrome is associated with [[myocardial infarction]] (heart attack), and with [[cardiac surgery|heart surgery]].
==Differential diagnosis==
In the setting of myocardial infarction, Dressler's syndrome occurs in about 7% of cases,<ref>{{cite journal | author = Krainin F, Flessas A, Spodick D | title = Infarction-associated pericarditis. Rarity of diagnostic electrocardiogram | journal = N Engl J Med | volume = 311 | issue = 19 | pages = 1211–4 | year = 1984 | pmid = 6493274}}</ref> and typically occurs 2 to 10 weeks after the myocardial infarction occurred. This differentiates Dressler's syndrome from the much more common post myocardial infarction pericarditis that occurs in 17 to 25% of cases of acute myocardial infarction and occurs between days 2 and 4 after the infarction. Dressler's syndrome also needs to be differentiated from pulmonary embolism, another identifiable cause of pleuritic (and non-pleuritic) chest pain in people who have been hospitalized and/or undergone surgical procedures within the preceding weeks.
==Treatment==
Dressler's syndrome is typically treated with [[Non-steroidal anti-inflammatory drug|NSAIDs]] such as [[aspirin]] or with [[corticosteroids]].<ref>{{cite journal | author = Gregoratos G | title = Pericardial involvement in acute myocardial infarction | journal = Cardiol Clin | volume = 8 | issue = 4 | pages = 601–8 | year = 1990 | pmid = 2249214}}</ref>
==See also==
==References==
<references/>
==External links==
* {{GPnotebook|-1140457467}}
*[http://www.antibodypatterns.com/cardiacmusclebody.php For antibody to cardiac muscle]
{{Circulatory system pathology}}
[[Category:Cardiology]]
[[de:Dressler-Syndrom]]
[[es:Síndrome de Dressler]]
[[pl:Zespół Dresslera]]
[[ru:Постинфарктный синдром]]