Dyslipidemia
513054
218904094
2008-06-12T18:14:40Z
203.134.146.126
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = |
Caption = |
DiseasesDB = |
ICD10 = {{ICD10|E|78||e|70}} |
ICD9 = {{ICD9|272}} |
ICDO = |
OMIM = |
MedlinePlus = |
eMedicineSubj = |
eMedicineTopic = |
MeshName = Dyslipidemias |
MeshNumber = C18.452.339 |
}}
'''Dyslipidemia''' is a disruption in the amount of [[lipids]] in the blood.
In western societies, most dyslipidemias are [[hyperlipidemia]]s; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia. Increased levels of [[OGT (gene)|O-GlcNAc transferase (OGT)]] are known to cause dylipidaemia.[http://www.nature.com/nature/journal/v451/n7181/edsumm/e080221-09.html]
==Classification==
There are two major ways in which dyslipidemias are classified:
* [[Phenotype]], or the presentation in the body (including the specific type of lipid that is increased)
* [[Etiology]], or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify.
==Types==
===Increases===
:''These conditions are discussed in greater detail at [[hyperlipidemia]].''
* Hyperlipidemia: [[lipids]]
** Hypercholesterolemia: [[cholesterol]]
** Hyperglyceridemia: [[glycerides]]
*** Hypertriglyceridemia: [[triglycerides]]
* Hyperlipoproteinemia: [[lipoproteins]] (usually [[LDL]] unless otherwise specified)
** Hyperchylomicronemia: [[chylomicrons]]
* Combined hyperlipidemia: both [[LDL]] and [[triglycerides]]
[[Familial hypercholesterolemia]] is a specific form of hypercholesterolemia due to a defect on [[chromosome 19]] (19p13.1-13.3).
===Decreases===
* [[Hypolipoproteinemia]]: [[lipoproteins]]
* [[Hypocholesterolemia]]: [[cholesterol]]
* [[Abetalipoproteinemia]]: beta [[lipoproteins]]
* [[Tangier disease]]: [[high density lipoprotein]]
{{med-stub}}
{{Lipid metabolism disorders}}
[[id:Dislipidemia]]
[[pt:Dislipidemia]]
[[sv:Dyslipidemi]]
[[vi:Rối loạn mỡ máu]]
[[zh:血脂障碍]]