Dyslipidemia 513054 218904094 2008-06-12T18:14:40Z 203.134.146.126 {{Infobox_Disease | Name = {{PAGENAME}} | Image = | Caption = | DiseasesDB = | ICD10 = {{ICD10|E|78||e|70}} | ICD9 = {{ICD9|272}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshName = Dyslipidemias | MeshNumber = C18.452.339 | }} '''Dyslipidemia''' is a disruption in the amount of [[lipids]] in the blood. In western societies, most dyslipidemias are [[hyperlipidemia]]s; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia. Increased levels of [[OGT (gene)|O-GlcNAc transferase (OGT)]] are known to cause dylipidaemia.[http://www.nature.com/nature/journal/v451/n7181/edsumm/e080221-09.html] ==Classification== There are two major ways in which dyslipidemias are classified: * [[Phenotype]], or the presentation in the body (including the specific type of lipid that is increased) * [[Etiology]], or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify. ==Types== ===Increases=== :''These conditions are discussed in greater detail at [[hyperlipidemia]].'' * Hyperlipidemia: [[lipids]] ** Hypercholesterolemia: [[cholesterol]] ** Hyperglyceridemia: [[glycerides]] *** Hypertriglyceridemia: [[triglycerides]] * Hyperlipoproteinemia: [[lipoproteins]] (usually [[LDL]] unless otherwise specified) ** Hyperchylomicronemia: [[chylomicrons]] * Combined hyperlipidemia: both [[LDL]] and [[triglycerides]] [[Familial hypercholesterolemia]] is a specific form of hypercholesterolemia due to a defect on [[chromosome 19]] (19p13.1-13.3). ===Decreases=== * [[Hypolipoproteinemia]]: [[lipoproteins]] * [[Hypocholesterolemia]]: [[cholesterol]] * [[Abetalipoproteinemia]]: beta [[lipoproteins]] * [[Tangier disease]]: [[high density lipoprotein]] {{med-stub}} {{Lipid metabolism disorders}} [[id:Dislipidemia]] [[pt:Dislipidemia]] [[sv:Dyslipidemi]] [[vi:Rối loạn mỡ máu]] [[zh:血脂障碍]]