Ecdysone 420624 218740672 2008-06-11T23:27:29Z Giancarlodessi 3669718 +[[it:Ecdisone]] {{Chembox new | ImageFile = Ecdysone.svg | ImageSize = 200px | IUPACName = <small>(2''S'',3''R'',5''R'',9''R'',10''R'',13''R'',14''S'',17''R'')-17- [(2''S'',3''R'')-3,6-dihydroxy-6-methylheptan- 2-yl]-2,3,14-trihydroxy-10,13-dimethyl- 2,3,4,5,9,11,12,15,16,17-decahydro- 1''H''-cyclopenta[a]phenanthren-6-one</small> | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = 3604-87-3 | PubChem = 19212 | SMILES = C[C@@H]([C@H]1CC[C@@]2([C@@]1 (CC[C@H]3C2=CC(=O)[C@H]4[C@@]3 (C[C@@H]([C@@H](C4)O)O)C)C)O) [C@@H](CCC(C)(C)O)O }} | Section2 = {{Chembox Properties | Formula = C<sub>27</sub>H<sub>44</sub>O<sub>6</sub> | MolarMass = 464.63 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | Autoignition = }} }} '''Ecdysone''' is a [[steroid]]al [[prohormone]] of the major insect [[ecdysis|moulting]] hormone [[20-hydroxyecdysone]], which is secreted from the [[prothoracic gland]]s. Insect moulting hormones (ecdysone and its homologues) are generally called [[ecdysteroid]]s. Ecdysteroids act as moulting hormones of [[arthropod]]s but also occur in other related [[phylum]]s where they can play different role. In ''[[Drosophila melanogaster]]'' ecdysone concentration increase induces the expression of genes coding for proteins that the larva requires, and it cause chromosome puffs (sites of high expression) to form. Ecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivorous insects. These [[phytoecdysteroid]]s have medicinal value{{Fact|date=April 2008}} and are part of herbal [[adaptogen]]ic remedies like [[Cordyceps]]. A pesticide sold with the name MIMIC has ecdysteroid activity, although its chemical structure has little resemblance to the ecdysteroids. ==See also== * [[Ecdysone receptor]] ==External links== * [http://ecdybase.org/ Ecdybase], The Ecdysone Handbook - a free online ecdysteroids database [[Category:Entomology]] [[Category:Steroids]] {{arthropod-stub}} [[de:Ecdyson]] [[fr:Ecdysone]] [[it:Ecdisone]] [[ja:エクジソン]] [[pl:Ekdyzon]]