Entner–Doudoroff pathway
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221782039
2008-06-26T02:11:57Z
Isolation booth
7263958
moved [[Entner-Doudoroff Pathway]] to [[Entner–Doudoroff pathway]]
[[Image:Entner-Doudoroff_pathway.jpg|thumb|600px|right|Diagram of the Entner-Doudoroff Pathway]]
The '''Entner-Doudoroff pathway''' describes an alternate series of reactions that catabolize [[glucose]] to [[pyruvate]] using a set of enzymes different from those used in either [[glycolysis]] or the [[pentose phosphate pathway]]. Most bacteria use glycolysis and the pentose phosphate pathway.
Distinct features of the Entner-Doudoroff pathway are that it:
* Occurs only in [[prokaryotes]].
* Uses 6-phosphogluconate dehydrase and 2-keto-3-deoxyglucosephophate aldolase to create pyruvates from glucose.
* Does not produce gases during its metabolic process, distinguishing them from microorganisms of enteric species.
* Has a net yield of 1 ATP for every [[glucose]] molecule processed, as well as 1 [[NADH]] and 1 [[NADPH]]. By comparison, glycolysis has a net yield of 2 [[adenosine triphosphate|ATP]] and 2 NADH for every one [[glucose]] molecule processed.
==Organisms that utilize the Entner-Doudoroff pathway==
There are a few bacteria that substitute [[Glycolysis|classic glycolysis]] with the Entner-Doudoroff Pathway. They may lack enzymes essential for glycolysis, such as [[phosphofructokinase-1]]. Most organisms that use the pathway are [[Aerobic_organism|aerobes]] due to the low ATP yield per glucose. <ref> [http://www.ias.ac.in/currsci/jul10/articles14.htm Zymomonas mobilis] </ref>
* ''[[Pseudomonas aeruginosa]]'', a Gram-negative bacteria
* ''[[Azotobacter]]'', a Gram-negative bacteria
* ''[[Rhizobium]]'', a Gram-negative bacteria
* ''[[Enterococcus faecalis]]'', a Gram-positive bacteria
* ''[[Zymomonas mobilis]]'', an ''[[Anaerobic_organism|anaerobic]]'' organism
==References==
Mohamed, M. Optometry Professor. Smith, K. Optometrist. Sohn, S. Biomedical Science Professor.
<references/>
==External links==
* [http://www.dbs.umt.edu/courses/fall2006/bioc380/lectures/033/lecture.html#Section%2011.7:%20The%20Entner-Doudoroff%20Pathway Diagram at umt.edu]
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[[Category:Metabolic pathways]]
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