Entner–Doudoroff pathway 997986 221782039 2008-06-26T02:11:57Z Isolation booth 7263958 moved [[Entner-Doudoroff Pathway]] to [[Entner–Doudoroff pathway]] [[Image:Entner-Doudoroff_pathway.jpg|thumb|600px|right|Diagram of the Entner-Doudoroff Pathway]] The '''Entner-Doudoroff pathway''' describes an alternate series of reactions that catabolize [[glucose]] to [[pyruvate]] using a set of enzymes different from those used in either [[glycolysis]] or the [[pentose phosphate pathway]]. Most bacteria use glycolysis and the pentose phosphate pathway. Distinct features of the Entner-Doudoroff pathway are that it: * Occurs only in [[prokaryotes]]. * Uses 6-phosphogluconate dehydrase and 2-keto-3-deoxyglucosephophate aldolase to create pyruvates from glucose. * Does not produce gases during its metabolic process, distinguishing them from microorganisms of enteric species. * Has a net yield of 1 ATP for every [[glucose]] molecule processed, as well as 1 [[NADH]] and 1 [[NADPH]]. By comparison, glycolysis has a net yield of 2 [[adenosine triphosphate|ATP]] and 2 NADH for every one [[glucose]] molecule processed. ==Organisms that utilize the Entner-Doudoroff pathway== There are a few bacteria that substitute [[Glycolysis|classic glycolysis]] with the Entner-Doudoroff Pathway. They may lack enzymes essential for glycolysis, such as [[phosphofructokinase-1]]. Most organisms that use the pathway are [[Aerobic_organism|aerobes]] due to the low ATP yield per glucose. <ref> [http://www.ias.ac.in/currsci/jul10/articles14.htm Zymomonas mobilis] </ref> * ''[[Pseudomonas aeruginosa]]'', a Gram-negative bacteria * ''[[Azotobacter]]'', a Gram-negative bacteria * ''[[Rhizobium]]'', a Gram-negative bacteria * ''[[Enterococcus faecalis]]'', a Gram-positive bacteria * ''[[Zymomonas mobilis]]'', an ''[[Anaerobic_organism|anaerobic]]'' organism ==References== Mohamed, M. Optometry Professor. Smith, K. Optometrist. Sohn, S. Biomedical Science Professor. <references/> ==External links== * [http://www.dbs.umt.edu/courses/fall2006/bioc380/lectures/033/lecture.html#Section%2011.7:%20The%20Entner-Doudoroff%20Pathway Diagram at umt.edu] {{micro-stub}} [[Category:Metabolic pathways]] [[de:Entner-Doudoroff-Weg]] [[fr:Entner-Doudoroff]]