Eosinophilia 238806 218602729 2008-06-11T11:09:49Z Miguel Andrade 569674 /* Causes */ fixed one link {{DiseaseDisorder infobox | Name = Eosinophilia | ICD10 = {{ICD10|D|72|1|d|70}} | ICD9 = {{ICD9|288.3}} | ICDO = | Image = | Caption = | OMIM = | MedlinePlus = | eMedicineSubj = med | eMedicineTopic = 685 | DiseasesDB = 4328 | MeshID = D004802 | }} '''Eosinophilia''' is the state of having a high concentration of '''eosinophils''' ([[eosinophil granulocyte]]s) in the [[blood]]. The normal concentration is between 0 and 0.5 x 10<sup>9</sup> eosinophils per [[litre]] of blood. Eosinophilia can be ''reactive'' (in response to other stimuli such as allergy or infection) or ''non reactive''. The release of [[interleukin 5]] by [[T cell]]s, [[mast cell]]s and [[macrophage]]s stimulates the production of eosinophils. ==Causes== Diseases that feature eosinophilia: * [[Hypereosinophilic syndrome]] * [[Parasite|Parasitic infection]]s (intestinal [[helminth]]iasis) * [[allergy|Allergic disorders]] * Some [[drug reaction]]s * [[Cholesterol emboli]]zation * [[Churg-Strauss syndrome]] * Some forms of [[chronic myeloid leukaemia]] * [[Hodgkin's disease]] * [[Gleich's syndrome]] * [[Addison's disease]] * [[Clonorchis sinensis]], a type of flatworm ==Management== If eosinophilia persists for six months, and all major recognized secondary causes have been excluded (parasitic/helminthic infections, HIV, drug hypersensitivity, cancer, lymphomas, and primary allergic disorders), the diagnosis of idiopathic eosinophilia is made. It is modified to [[hypereosinophilic syndrome]] if there is evidence of organ involvement.<ref name="pmid16750989">{{cite journal |author=Klion AD, Bochner BS, Gleich GJ, ''et al'' |title=Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report |journal=J. Allergy Clin. Immunol. |volume=117 |issue=6 |pages=1292-302 |year=2006 |pmid=16750989 |doi=10.1016/j.jaci.2006.02.042| url=http://www.jacionline.org/article/PIIS0091674906005203/fulltext}}</ref> ==See also== * [[Eosinophilia-myalgia syndrome]] {{Hematology}} [[Category:Hematology]] [[cs:Eosinofilie]] [[de:Eosinophilie]] [[it:Eosinofilia]] [[nl:Eosinofilie]] [[pl:Eozynofilia]] [[pt:Eosinofilia]] [[sq:Eozinofilia]]