Formylation reaction
2570842
220558526
2008-06-20T13:03:16Z
Edgar181
491706
minor cleanup; see also [[hydroformylation]]
[[Image:Aldehyde2.png|thumb|right|100px|The formyl group]]
A '''formylation reaction''' in [[organic chemistry]] is the catch-all name for any [[organic reaction]] in which an [[organic compound]] is functionalized with a [[formyl]] group (-CH=O).
[[Aromatic]] formylation reactions via [[electrophilic aromatic substitution]] include:
* [[Dimethylformamide]] and [[phosphorus oxychloride]] in the [[Vilsmeier-Haack reaction]]
* [[Hexamine]] in the [[Duff reaction]] and the [[Sommelet reaction]]
* [[Carbon monoxide]] and [[hydrochloric acid]] in the [[Gattermann-Koch reaction]]
* [[Zinc cyanide]] and [[hydrochloric acid]] in the [[Gatterman aldehyde synthesis]]
* [[Chloroform]] in the [[Reimer-Tiemann reaction]]
In biological systems, [[formylation]] is one of the processes of [[posttranslational modification]] in which a formyl group is added to the N-terminus of a protein.
==See also==
* [[Hydroformylation]]
[[category:Substitution reactions]]
[[ja:ホルミル化]]