Formylation reaction 2570842 220558526 2008-06-20T13:03:16Z Edgar181 491706 minor cleanup; see also [[hydroformylation]] [[Image:Aldehyde2.png|thumb|right|100px|The formyl group]] A '''formylation reaction''' in [[organic chemistry]] is the catch-all name for any [[organic reaction]] in which an [[organic compound]] is functionalized with a [[formyl]] group (-CH=O). [[Aromatic]] formylation reactions via [[electrophilic aromatic substitution]] include: * [[Dimethylformamide]] and [[phosphorus oxychloride]] in the [[Vilsmeier-Haack reaction]] * [[Hexamine]] in the [[Duff reaction]] and the [[Sommelet reaction]] * [[Carbon monoxide]] and [[hydrochloric acid]] in the [[Gattermann-Koch reaction]] * [[Zinc cyanide]] and [[hydrochloric acid]] in the [[Gatterman aldehyde synthesis]] * [[Chloroform]] in the [[Reimer-Tiemann reaction]] In biological systems, [[formylation]] is one of the processes of [[posttranslational modification]] in which a formyl group is added to the N-terminus of a protein. ==See also== * [[Hydroformylation]] [[category:Substitution reactions]] [[ja:ホルミル化]]