Fundic glands
4733250
217839274
2008-06-07T22:49:28Z
ClueBot
4928500
Reverting possible vandalism by [[Special:Contributions/76.175.223.149|76.175.223.149]] to version by ELLusKa 86. False positive? [[User:ClueBot/FalsePositives|Report it]]. Thanks, [[User:ClueBot]]. (409900) (Bot)
{{Infobox Anatomy |
Name = Fundic glands |
Latin = glandulae gastricae |
GraySubject = 247 |
GrayPage = 1166 |
Image = Fundic gland polyp (1).jpg |
Caption = H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation |
Image2 = |
Caption2 = |
System = |
MeshName = |
MeshNumber = |
DorlandsPre = g_06 |
DorlandsSuf = 12391406 |
}}
The '''fundus glands''' (or '''fundic glands''', or '''gastric glands''') are found in the [[Body of stomach|body]] and [[Fundus (stomach)|fundus]] of the [[stomach]].
They are simple tubes, two or more of which open into a single duct.
==Pathology==
[[Fundic gland polyposis]] is a medical syndrome where the [[fundus]] of the [[stomach]] develops many [[polyp (medicine)|polyps]].
==Types of cells==
{| class="wikitable"
| '''Location''' || '''Name''' || '''Description''' || '''Secretion''' || '''Staining'''
|-
| Isthmus || [[mucous cells]] || In [[gastric pits]]. || [[mucus]] gel layer || Clear
|-
| Neck || [[parietal cell|parietal (oxyntic) cell]]s || Between the chief cells and the [[basement membrane]], larger oval cells, which stain deeply with [[eosin]], are found; these cells are studded throughout the tube at intervals, giving it a beaded or [[varicose]] appearance. These are known as the ''[[parietal cells]]'' or ''oxyntic cells'', and they are connected with the lumen by fine channels which run into their substance. || [[gastric acid]] and [[intrinsic factor]] || [[Acidophilic]]
|-
| Base || [[Gastric chief cell|chief (zymogenic) cell]]s || At the point where they open into the duct, which is termed the neck, the [[epithelium]] alters, and consists of short columnar or polyhedral, granular cells, which almost fill the tube, so that the [[lumen]] becomes suddenly constricted and is continued down as a very fine channel. They are known as the ''[[chief cells]]'' or central cells of the glands. || [[pepsinogen]], [[rennin]] || [[Basophilic]]
|-
| Base || [[enteroendocrine cells|enteroendocrine (APUD) cells]] || - || [[hormones]] || -
|}
==Additional images==
<gallery>
Image:Gray1055.png|A fundus gland. A. Transverse section of gland.
Image:Illu stomach layers.jpg|Layers of stomach wall
</gallery>
==External links==
* {{eMedicineDictionary|gastric+glands}}
* {{OklahomaHistology|50_02}} - "Fundic stomach"
* {{UCDavisOrganology|Digestive/mammal/stomach4/stomach2}} - "Mammal, ruminant stomach (LM, High)"
* {{BUHistology|11301ooa}} - "Digestive System: Alimentary Canal - fundic stomach"
* [http://education.vetmed.vt.edu/curriculum/VM8054/Labs/Lab18/EXAMPLES/Exfndgld.htm Veterinary Histology at vt.edu]
* {{LoyolaMedEd|Histo/frames/Histo18.html}} - see slide #42
{{Gray's}}
{{Digestive tract}}
{{digestive-stub}}
[[fi:Maharauhanen]]