Fundic glands 4733250 217839274 2008-06-07T22:49:28Z ClueBot 4928500 Reverting possible vandalism by [[Special:Contributions/76.175.223.149|76.175.223.149]] to version by ELLusKa 86. False positive? [[User:ClueBot/FalsePositives|Report it]]. Thanks, [[User:ClueBot]]. (409900) (Bot) {{Infobox Anatomy | Name = Fundic glands | Latin = glandulae gastricae | GraySubject = 247 | GrayPage = 1166 | Image = Fundic gland polyp (1).jpg | Caption = H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation | Image2 = | Caption2 = | System = | MeshName = | MeshNumber = | DorlandsPre = g_06 | DorlandsSuf = 12391406 | }} The '''fundus glands''' (or '''fundic glands''', or '''gastric glands''') are found in the [[Body of stomach|body]] and [[Fundus (stomach)|fundus]] of the [[stomach]]. They are simple tubes, two or more of which open into a single duct. ==Pathology== [[Fundic gland polyposis]] is a medical syndrome where the [[fundus]] of the [[stomach]] develops many [[polyp (medicine)|polyps]]. ==Types of cells== {| class="wikitable" | '''Location''' || '''Name''' || '''Description''' || '''Secretion''' || '''Staining''' |- | Isthmus || [[mucous cells]] || In [[gastric pits]]. || [[mucus]] gel layer || Clear |- | Neck || [[parietal cell|parietal (oxyntic) cell]]s || Between the chief cells and the [[basement membrane]], larger oval cells, which stain deeply with [[eosin]], are found; these cells are studded throughout the tube at intervals, giving it a beaded or [[varicose]] appearance. These are known as the ''[[parietal cells]]'' or ''oxyntic cells'', and they are connected with the lumen by fine channels which run into their substance. || [[gastric acid]] and [[intrinsic factor]] || [[Acidophilic]] |- | Base || [[Gastric chief cell|chief (zymogenic) cell]]s || At the point where they open into the duct, which is termed the neck, the [[epithelium]] alters, and consists of short columnar or polyhedral, granular cells, which almost fill the tube, so that the [[lumen]] becomes suddenly constricted and is continued down as a very fine channel. They are known as the ''[[chief cells]]'' or central cells of the glands. || [[pepsinogen]], [[rennin]] || [[Basophilic]] |- | Base || [[enteroendocrine cells|enteroendocrine (APUD) cells]] || - || [[hormones]] || - |} ==Additional images== <gallery> Image:Gray1055.png|A fundus gland. A. Transverse section of gland. Image:Illu stomach layers.jpg|Layers of stomach wall </gallery> ==External links== * {{eMedicineDictionary|gastric+glands}} * {{OklahomaHistology|50_02}} - "Fundic stomach" * {{UCDavisOrganology|Digestive/mammal/stomach4/stomach2}} - "Mammal, ruminant stomach (LM, High)" * {{BUHistology|11301ooa}} - "Digestive System: Alimentary Canal - fundic stomach" * [http://education.vetmed.vt.edu/curriculum/VM8054/Labs/Lab18/EXAMPLES/Exfndgld.htm Veterinary Histology at vt.edu] * {{LoyolaMedEd|Histo/frames/Histo18.html}} - see slide #42 {{Gray's}} {{Digestive tract}} {{digestive-stub}} [[fi:Maharauhanen]]