Glucose-1-phosphate 1592907 218589328 2008-06-11T09:25:23Z 60.241.34.151 /* Catabolic */ {{Chembox new | ImageFile = Cori ester.svg | ImageSize = 150px | ImageFile2 = Cori ester.gif | ImageSize2 = 150px | IUPACName = | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = 59-56-3 | PubChem = 65533 | SMILES = | MeSHName = glucose-1-phosphate }} | Section2 = {{Chembox Properties | Formula = C6H13O9P | MolarMass = 260.136 | Appearance = | Density = | MeltingPt = | BoilingPt = }} | Section3 = {{Chembox Hazards | Solubility = | MainHazards = | FlashPt = | Autoignition = }} }} '''Glucose 1-phosphate''' (also called '''cori ester''') is a [[glucose]] molecule with a [[phosphate]] group on the 1'-carbon. ==Reactions== ===Catabolic=== In [[glycogenolysis]], it is the direct product of the reaction in which [[glycogen phosphorylase]] cleaves off a [[molecule]] of [[glucose]] from a greater [[glycogen]] structure. To be utilized in cellular catabolism it must first be converted to [[glucose 6-phosphate]] by the [[enzyme]] [[phosphoglucomutase]]. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism. ===Anabolic=== In [[glycogenesis]], free glucose 1-phosphate can also react with [[UTP]] to form [[UDP-glucose]], by using the enzyme [[UDP-glucose pyrophosphorylase]]. It can then return to the greater glycogen structure via [[glycogen synthase]]. ==See also== * [[Pentose phosphate pathway]] ==External links== [[Category:Organophosphates]] [[Category:Monosaccharides]] {{biochem-stub}} [[ja:グルコース-1-リン酸]]