Glucose-1-phosphate
1592907
218589328
2008-06-11T09:25:23Z
60.241.34.151
/* Catabolic */
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| ImageFile = Cori ester.svg
| ImageSize = 150px
| ImageFile2 = Cori ester.gif
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| Section1 = {{Chembox Identifiers
| CASNo = 59-56-3
| PubChem = 65533
| SMILES =
| MeSHName = glucose-1-phosphate
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| Section2 = {{Chembox Properties
| Formula = C6H13O9P
| MolarMass = 260.136
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| Section3 = {{Chembox Hazards
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'''Glucose 1-phosphate''' (also called '''cori ester''') is a [[glucose]] molecule with a [[phosphate]] group on the 1'-carbon.
==Reactions==
===Catabolic===
In [[glycogenolysis]], it is the direct product of the reaction in which [[glycogen phosphorylase]] cleaves off a [[molecule]] of [[glucose]] from a greater [[glycogen]] structure.
To be utilized in cellular catabolism it must first be converted to [[glucose 6-phosphate]] by the [[enzyme]] [[phosphoglucomutase]]. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.
===Anabolic===
In [[glycogenesis]], free glucose 1-phosphate can also react with [[UTP]] to form [[UDP-glucose]], by using the enzyme [[UDP-glucose pyrophosphorylase]]. It can then return to the greater glycogen structure via [[glycogen synthase]].
==See also==
* [[Pentose phosphate pathway]]
==External links==
[[Category:Organophosphates]]
[[Category:Monosaccharides]]
{{biochem-stub}}
[[ja:グルコース-1-リン酸]]