Hyperchloremic acidosis 3233799 222730716 2008-06-30T20:52:21Z Oobopshark 35713 {{DiseaseDisorder infobox | Name = Hyperchloremic acidosis | ICD10 = {{ICD10|E|87|2|e|70}} | ICD9 = {{ICD9|276.2}} | Image = | Caption = | ICDO = | OMIM = | DiseasesDB = | MedlinePlus = | eMedicineSubj = med | eMedicineTopic = 1071 | }} '''Hyperchloremic acidosis''' is a form of [[metabolic acidosis]] associated with a normal [[anion gap]], a decrease in plasma [[bicarbonate]] concentration, and in an increase in plasma [[chloride]] concentration (see [[anion gap]] for a fuller explanation). ===Causes=== *[[Renal tubular acidosis]] failure of HCO<sub>3</sub><sup>-</sup> resorption(''i.e.'', proximal renal tubular acidosis) or failure of H<sup>+</sup> secretion (ie in distal renal tubular acidosis) *[[Renal failure]] *[[Gastrointestinal]] loss of HCO<sub>3</sub><sup>-</sup> with [[diarrhea]] (vomiting will tend to cause hypochloraemic [[alkalosis]]). *Ingestions **[[Ammonium chloride]], [[Hydrochloric acid]] **[[Hyperalimentation]] fluids (''i.e.'', [[total parenteral nutrition]]) * Alcohol (such as ethanol) can effect anion gap by inducing [[alcohol dehydrogenase]] enzyme. ==See also== *[[Anion gap]] *[[Metabolic acidosis]] ==External links== * {{FPnotebook|REN2}} * {{DiseasesDB|11673}} * [http://kidney.niddk.nih.gov/kudiseases/pubs/tubularacidosis/ NIH - Renal Tubular Acidosis] [[Category:Electrolyte disturbances]] [[Category:Nephrology]] {{med-stub}}