Hyperchloremic acidosis
3233799
222730716
2008-06-30T20:52:21Z
Oobopshark
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{{DiseaseDisorder infobox |
Name = Hyperchloremic acidosis |
ICD10 = {{ICD10|E|87|2|e|70}} |
ICD9 = {{ICD9|276.2}} |
Image = |
Caption = |
ICDO = |
OMIM = |
DiseasesDB = |
MedlinePlus = |
eMedicineSubj = med |
eMedicineTopic = 1071 |
}}
'''Hyperchloremic acidosis''' is a form of [[metabolic acidosis]] associated with a normal [[anion gap]], a decrease in plasma [[bicarbonate]] concentration, and in an increase in plasma [[chloride]] concentration (see [[anion gap]] for a fuller explanation).
===Causes===
*[[Renal tubular acidosis]] failure of HCO<sub>3</sub><sup>-</sup> resorption(''i.e.'', proximal renal tubular acidosis) or failure of H<sup>+</sup> secretion (ie in distal renal tubular acidosis)
*[[Renal failure]]
*[[Gastrointestinal]] loss of HCO<sub>3</sub><sup>-</sup> with [[diarrhea]] (vomiting will tend to cause hypochloraemic [[alkalosis]]).
*Ingestions
**[[Ammonium chloride]], [[Hydrochloric acid]]
**[[Hyperalimentation]] fluids (''i.e.'', [[total parenteral nutrition]])
* Alcohol (such as ethanol) can effect anion gap by inducing [[alcohol dehydrogenase]] enzyme.
==See also==
*[[Anion gap]]
*[[Metabolic acidosis]]
==External links==
* {{FPnotebook|REN2}}
* {{DiseasesDB|11673}}
* [http://kidney.niddk.nih.gov/kudiseases/pubs/tubularacidosis/ NIH - Renal Tubular Acidosis]
[[Category:Electrolyte disturbances]]
[[Category:Nephrology]]
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