Impaired fasting glycaemia
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225428945
2008-07-13T17:24:32Z
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{{Diabetes}}
'''Impaired fasting glycaemia''' (IFG) is a pre-diabetic state of dysglycemia, associated with insulin resistance and increased risk of cardiovascular pathology, although of lesser risk than [[Impaired glucose tolerance]] (IGT). IFG often progresses to [[type 2 diabetes mellitus]], a recent study citing the average time for progression as less than three years.<ref>{{cite journal |author=Nichols GA, Hillier TA, Brown JB| title=Progression From Newly Acquired Impaired Fasting Glusose to Type 2 Diabetes |journal=Diabetes Care |volume=30 |pages=228–233 |year=2007 |url=http://care.diabetesjournals.org/cgi/content/full/30/2/228| doi=10.2337/dc06-1392| pmid=17259486}}</ref> IFG is also a risk factor for mortality.<ref name="pmid17576864">{{cite journal |author=Barr EL, Zimmet PZ, Welborn TA, ''et al'' |title=Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance: the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab) |journal=Circulation |volume=116 |issue=2 |pages=151–7 |year=2007 |pmid=17576864 |doi=10.1161/CIRCULATIONAHA.106.685628}}</ref>
It is characterised by an intermediately raised [[fasting]] [[glucose]] level, but less than would qualify for type 2 diabetes mellitus. On challenging with an [[oral glucose tolerance test]], normal blood glucose levels are maintained after 2 hours, unlike IGT.
===Criteria===
* [[fasting]] [[glucose]] level > 5.6 mmol/l (100 mg/dl) and < 6.9 mmol/l (125mg/dl).<ref name="who-99">.{{cite web |url=http://www.who.int/diabetes/publications/en/ |author=[[World Health Organization]] | title= Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus |accessdate=2007-05-29 |format= |work=}}</ref><ref name="pmid15618111">{{cite journal |author= |title=Diagnosis and classification of diabetes mellitus |journal=Diabetes Care |volume=28 Suppl 1 |issue= |pages=S37–42 |year=2005 |pmid=15618111 |doi=}}</ref>
The criteria will continue to change as many endocrinologists believe an impaired fasting glycose may eventually include fasting glucose between a high 95-100 mg/dl.{{fact|date=May 2008}}
==References==
{{reflist}}
==See also==
* [[Impaired glucose tolerance]]
* [[Glucose tolerance test]]
[[Category:Endocrinology]]
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[[ar:اختلال سكر الدم على الريق]]
[[pl:Nieprawidłowa glikemia na czczo]]
[[zh:空腹血糖异常]]