Jacqueline Barton
1166876
220986673
2008-06-22T15:03:26Z
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{{Infobox Scientist
|image = Replace this image female.svg <!-- only free-content images are allowed for depicting living people - see [[WP:NONFREE]] -->
|image_width = 150px |
|name=Jacqueline K. Barton
|birth_date=
|birth_place=[[New York City]]
|nationality=USA
|field=Chemistry
|alma_mater=[[Barnard College]]<br>[[Columbia University|Columbia]]
|work_institution=[[Bell Telephone Laboratories|Bell Labs]]<br>[[Yale University|Yale]]<br>[[Hunter College]]<br>[[Columbia University|Columbia]]<br>[[Caltech]]
|doctoral_supervisor=[[S.J. Lippard]]
|doctoral_students=[[Anna Marie Pyle]]
|societies=[[American Academy of Arts and Sciences]]
[[American Philosophical Society]]
[[National Academy of Sciences]]
|prizes=[[Alan T. Waterman]] Award of the [[National Science Foundation]] (1985)
[[Fresenius Award]] (1986)
[[American Chemical Society]] [[Eli Lilly]] Award in Biological Chemistry(1987)
American Chemical Society Award in Pure Chemistry (1988)
The Mayor of New York's Award in Science and Technology (1988)
American Chemical Society Baekeland Medal (1991)
[[MacArthur Foundation]] Fellowship (1991)
American Chemical Society [[Garvan-Olin Medal|Garvan Medal]] (1992)
American Chemical Society Tolman Medal (1994)
Havinga Medal (1995)
Paul Karrer Medal (1996)
American Chemical Society Nichols Medal (1997)
[[Weizmann Women & Science Award]] (1998)
ACS Ronald Breslow Award in Biomimetic Chemistry (2003)
[[Willard Gibbs Award|ACS Gibbs Medal]] (2006)
}}
Professor '''Jacqueline K. Barton''' is the Arthur and Marian Hanisch Memorial professor of [[Chemistry]] at [[California Institute of Technology]]. The primary focus of her research is transverse electron transport along double-stranded [[DNA]], its implications in the biology of DNA damage and repair, and its potential for [[materials science]]s applications. She is married to fellow Caltech chemist [[Peter Dervan]].
==Education==
Barton received her B.A. (summa cum laude) from [[Barnard College]] in 1974. She went on to graduate study at [[Columbia University]], where she studied inorganic chemistry under the supervision of [[S.J. Lippard]]. After earning her Ph.D. from Columbia in 1979, she held post-doctoral appointments at [[Bell Telephone Laboratories|Bell Labs]] and [[Yale University]], where she worked with [[R.G. Shulman]].
==Selected publications==
* {{cite journal
|title=Direct Electrochemistry of Endonuclease III in the Presence and Absence of DNA
|first=A.A.
|last=Gorodetsky
|coauthors=A.K. Boal, and J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=128
|pages=12082–12083
|year=2006
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A253.pdf
|doi=10.1021/ja064784d
|format=abstract}}
* {{cite journal
|title=Electrochemistry Using Self-Assembled DNA Monolayers on Highly Oriented Pyrolytic Graphite
|first=A.A.
|last=Gorodetsky
|coauthors=J.K. Barton
|journal=Langmuir
|volume=22
|pages=7917–7922
|year=2006
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A252.pdf
|doi=10.1021/la0611054
|format=abstract}}
* {{cite journal
|title=Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF Mass Spectrometry
|first=J.
|last=Brunner
|coauthors=J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=128
|pages=6772–6773
|year=2006
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A251.pdf
|doi=10.1021/ja0612753
|format=abstract}}
* {{cite journal
|title=Electron Trap for DNA-bound Repair Enzymes: A Strategy For DNA-mediated Signaling
|first=E.
|last=Yavin
|coauthors=E.D.A. Stemp, V.L. O'Shea, S.S. David and J.K. Barton
|journal=Proc. Nat. Acad. Sci. USA
|volume=103
|pages=3610–3614
|year=2006
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A250.pdf
|doi=10.1073/pnas.0600239103
|format=abstract
|pmid=16505354}}
* {{cite journal
|title=A Mismatch-Selective Bifunctional Rhodium-Oregon Green Conjugate: A Fluorescent Probe for Mismatched DNA
|first=B.M.
|last=Zeglis
|coauthors=J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=128
|pages=5654–5655
|year=2006
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A249.pdf
|doi=10.1021/ja061409c
|format=abstract}}
* {{cite journal
|title=Sequence Dependence of Charge Transport through DNA Domains
|first=F.
|last=Shao
|coauthors=K. Augustyn and J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=127
|pages=17445–17452
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A248.pdf
|doi=10.1021/ja0563399
|format=abstract}}
* {{cite journal
|title=Reductive and Oxidative DNA Damage by Photoactive Platinum(II) Intercalators
|first=W.
|last=Lu
|coauthors=D.A. Vicic, and J.K. Barton
|journal=Inorg. Chem.
|volume=44
|pages=7970–7980
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A247.pdf
|doi=10.1021/ic051124l
|format=abstract}}
* {{cite journal
|title=DNA Charge Transport Leading to Disulfide Bond Formation
|first=T.
|last=Takada
|coauthors=J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=127
|pages=12204–12205
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A246.pdf
|doi=10.1021/ja054306n
|format=abstract}}
* {{cite journal
|title=Electrochemically Monitoring DNA Repair by Photolyase
|first=M.C.
|last=DeRosa
|coauthors=A. Sancar, and J.K. Barton
|journal=Proc. Nat. Acad. Sci. USA
|volume=102
|pages=10788–10792
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A245.pdf
|doi=10.1073/pnas.0503527102
|format=abstract
|pmid=16043698}}
* {{cite book
|chapter=Sequence-Dependent DNA Dynamics: The Regulator of DNA-Mediated Charge Transport
|first=M.A.
|last=O'Neill
|coauthors=J.K. Barton
|title=Charge Transfer in DNA: From Mechanism to Application
|editor=ed. H.A. Wagenknecht
|publisher=Wiley-VCH
|pages=27-75
|year=2005}}
* {{cite journal
|title=DNA Electrochemistry through the Base Pairs Not the Sugar-Phosphate Backbone
|first=T.
|last=Liu
|coauthors=J.K. Barton
|journal=J. Am. Chem. Soc.
|volume=127
|pages=10160–10161
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A244.pdf
|doi=10.1021/ja053025c
|format=abstract}}
* {{cite journal
|title=DNA-Bound Redox Activity of DNA Repair Glycosylases Containing [4Fe-4S] Clusters
|first=A.K.
|last=Boal
|coauthors=E. Yavin, O.A. Lukianova, V.L. O'Shea, S.S. David, and J.K. Barton
|journal=Biochem.
|volume=44
|pages=8397–8407
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A243.pdf
|doi=10.1021/bi047494n
|format=abstract}}
* {{cite journal
|title=Electrochemical Detection of Lesions in DNA
|first=A.K.
|last=Boal
|coauthors=J.K. Barton
|journal=Bioconj. Chem.
|volume=16
|pages=312–321
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A242.pdf
|doi=10.1021/bc0497362
|format=abstract}}
* {{cite journal
|title=Protein-DNA Charge Transport: Redox Activation of a DNA Repair Protein by Guanine Radical
|first=E.
|last=Yavin
|coauthors=A.K. Boal, E.D.A. Stemp, E.M. Boon, A.L. Livingston, V.L. O'Shea, S.S. David, and J.K. Barton
|journal=Proc. Nat. Acad. Sci. USA
|volume=102
|pages=3546–3551
|year=2005
|url=http://www.its.caltech.edu/~jkbgrp/abstracts/A241.pdf
|doi=10.1073/pnas.0409410102
|format=abstract
|pmid=15738421}}
==External links==
*[http://www.its.caltech.edu/~jkbgrp/TheBoss.htm Personal biography]
*[http://www.its.caltech.edu/~jkbgrp/ Barton Research Group]
{{Dow Chemical}}
<!-- Metadata: see [[Wikipedia:Persondata]] -->
{{Persondata
|NAME= Barton, Jacqueline K.
|ALTERNATIVE NAMES=
|SHORT DESCRIPTION=[[United States|American]] chemist
|DATE OF BIRTH=
|PLACE OF BIRTH=[[New York City]]
|DATE OF DEATH=
|PLACE OF DEATH=
}}
{{DEFAULTSORT:Barton, Jacqueline}}
[[Category:1952 births]]
[[Category:Members of the National Academy of Sciences]]
[[Category:Barnard College alumni]]
[[Category:Living people]]
[[Category:American chemists]]
[[Category:MacArthur Fellows]]
[[Category:Dow Chemical Company]]
[[Category:California Institute of Technology faculty]]