John Jacob Abel
1149742
223252399
2008-07-03T07:15:16Z
Waacstats
1951353
Stub-sorting. [[Wikipedia:WikiProject Stub sorting|You can help!]]
{{Infobox Scientist
|name = John Jacob Abel
|box_width =
|image =Replace_this_image_male.svg
|image_width =150px
|caption = John Jacob Abel
|birth_date = [[May 19]], [[1857]]
|birth_place = [[Cleveland, Ohio|Cleveland]], [[Ohio]]
|death_date = [[May 26]], [[1938]]
|death_place =
|residence =
|citizenship =
|nationality = [[United States of America|American]]
|ethnicity =
|field = [[biochemistry|biochemist]]<br/>[[pharmacology|pharmacologist]]
|work_institutions =
|alma_mater = [[University of Michigan]]
|doctoral_advisor =
|doctoral_students =
|known_for =
|author_abbrev_bot =
|author_abbrev_zoo =
|influences =
|influenced =
|prizes =
|religion =
|footnotes =
|signature =
}}
'''John Jacob Abel''' ([[May 19]], [[1857]] – [[May 26]], [[1938]]) was a significant [[United States of America|American]] [[biochemistry|biochemist]] and [[pharmacology|pharmacologist]].
Born near [[Cleveland, Ohio|Cleveland]], [[Ohio]], he graduated with a Ph.D. 1883 from the [[University of Michigan]]. In [[1891]] he founded and chaired the first department of pharmacology in the United States at the University of Michigan. In [[1893]], he went on to chair the pharmacology department at [[Johns Hopkins University]]. In [[1897]], he was the second to isolate [[epinephrine]], also known as adrenaline (the first was [[Napoleon Cybulski]] in 1895), although the extracts he produced have been shown to be mostly an inactive metabolite and the first pure extracts were produced by the Japanese [[Jokichi Takamine]] (1854-1922) who patented the formulation under the name '''adrenalin'''. He later formulated the idea of the artificial [[kidney]] and in [[1914]] he isolated [[amino acids]] from the [[blood]].
He spent years unsuccessfully searching for the [[pituitary]] hormone, unaware that he was in fact looking for several hormones. In [[1926]], he reported the isolation and [[crystallization]] of [[insulin]], though this announcement was met with considerable scepticism and not generally accepted for many years.
Abel also co-founded the ''[[Journal of Biological Chemistry]]'' with [[Christian Archibald Herter (physician)|Christian Archibald Herter]] in [[1905]] and the ''Journal of Pharmacology and Experimental Therapeutics'' in [[1909]].
==References==
*{{Citation
|id = [[PMID]]:3517604
|url= http://www.ncbi.nlm.nih.gov/pubmed/3517604
|last=Gastel
|first=B
|publication-date=
|year=
|title=Abel and onward: some early history of hemodialysis.
|volume=20
|issue=2
|periodical=Medical instrumentation
|pages=62-4
}}
*{{Citation
|id = [[PMID]]:11615884
|url= http://www.ncbi.nlm.nih.gov/pubmed/11615884
|last=Becker
|first=R A
|publication-date=1982
|year=[[1982]]
|title=The John Jacob Abel papers--primary sources for the history of American pharmacology.
|volume=24
|issue=3
|periodical=Pharmacy in history
|pages=115-6
}}
*{{Citation
|id = [[PMID]]:6760940
|url= http://www.ncbi.nlm.nih.gov/pubmed/6760940
|last=Parascandola
|first=J
|publication-date=1982
|year=[[1982]]
|title=John J. Abel and the early development of pharmacology at the Johns Hopkins University.
|volume=56
|issue=4
|periodical=Bulletin of the history of medicine
|pages=512-27
}}
*{{Citation
|id = [[PMID]]:801548
|url= http://www.ncbi.nlm.nih.gov/pubmed/801548
|last=Harvey
|first=A M
|publication-date=1976
|year=[[1976]]
|title=Pharmacology's giant: John Jacob Abel.
|volume=
|issue=
|periodical=Johns Hopkins Med. J. Suppl.
|pages=49-59
}}
*{{Citation
|id = [[PMID]]:4606906
|url= http://www.ncbi.nlm.nih.gov/pubmed/4606906
|last=Harvey
|first=A M
|publication-date=1974 Oct
|year=[[1974]]
|title=Pharmacology's giant: John Jacob Abel.
|volume=135
|issue=4
|periodical=The Johns Hopkins medical journal
|pages=245-58
}}
* Rosenberg, Charles. "Abel, John Jacob." in ''[[Dictionary of Scientific Biography]].'' (1970). New York: Charles Scribner's Sons. Vol. 1: p.9-12.
*{{Citation
|id = [[PMID]]:5340582
|url= http://www.ncbi.nlm.nih.gov/pubmed/5340582
|last=Murnaghan
|first=J H
|last2=Talalay
|first2=P
|publication-date=1967
|year=[[1967]]
|title=John Jacob Abel and the crystallization of insulin.
|volume=10
|issue=3
|periodical=Perspect. Biol. Med.
|pages=334-80
}}
*{{Citation
|id = [[PMID]]:14118479
|url= http://www.ncbi.nlm.nih.gov/pubmed/14118479
|last=DARBY
|first=T D
|publication-date=1964 Feb
|year=[[1964]]
|title=ON TEACHING PHARMACOLOGY AND THERAPEUTICS IN OUR MEDICAL SCHOOLS. DELIBERATION UPON AND A REPHRASING OF AN ARTICLE BY JOHN J. ABEL.
|volume=67
|issue=
|periodical=Am. Heart J.
|pages=145-9
}}
*{{Citation
|id = [[PMID]]:13979597
|url= http://www.ncbi.nlm.nih.gov/pubmed/13979597
|last=SWAIN
|first=H H
|last2=Geiling
|first2=E M
|last3=Heingartner
|first3=A
|publication-date=
|year=
|title=John Jacob ABEL at Michigan. The introduction of pharmacology into the medical curriculum.
|volume=29
|issue=
|periodical=Medical bulletin (Ann Arbor, Mich.)
|pages=1-14
}}
*{{Citation
|id = [[PMID]]:13573011
|url= http://www.ncbi.nlm.nih.gov/pubmed/13573011
|last=MARSHALL
|first=E K
|publication-date=
|year=
|title=An exhibit at the centennial celebration of John Jacob Abel's birth.
|volume=32
|issue=4
|periodical=Bulletin of the history of medicine
|pages=356-65
}}
*{{Citation
|id = [[PMID]]:13489405
|url= http://www.ncbi.nlm.nih.gov/pubmed/13489405
|last=SOLLMAN
|first=T
|last2=AMBERG
|first2=S
|last3=VOEGTLIN
|first3=C
|last4=ROWNTREE
|first4=L G
|publication-date=1957 Dec
|year=[[1957]]
|title=Centenary of the birth of John Jacob Abel.
|volume=101
|issue=6
|periodical=Bulletin of the Johns Hopkins Hospital
|pages=298-328
}}
{{DEFAULTSORT:Abel, John Jacob}}
[[Category:American biochemists]]
[[Category:American pharmacologists]]
[[Category:1857 births]]
[[Category:1938 deaths]]
[[Category:Foreign Members of the Royal Society]]
{{US-biochemist-stub}}
[[cs:John Jacob Abel]]
[[de:John Jacob Abel]]
[[es:John Jacob Abel]]
[[it:John Jacob Abel]]
[[nl:John Jacob Abel]]
[[pt:John Jacob Abel]]
[[ro:John Jacob Abel]]