John Jacob Abel 1149742 223252399 2008-07-03T07:15:16Z Waacstats 1951353 Stub-sorting. [[Wikipedia:WikiProject Stub sorting|You can help!]] {{Infobox Scientist |name = John Jacob Abel |box_width = |image =Replace_this_image_male.svg |image_width =150px |caption = John Jacob Abel |birth_date = [[May 19]], [[1857]] |birth_place = [[Cleveland, Ohio|Cleveland]], [[Ohio]] |death_date = [[May 26]], [[1938]] |death_place = |residence = |citizenship = |nationality = [[United States of America|American]] |ethnicity = |field = [[biochemistry|biochemist]]<br/>[[pharmacology|pharmacologist]] |work_institutions = |alma_mater = [[University of Michigan]] |doctoral_advisor = |doctoral_students = |known_for = |author_abbrev_bot = |author_abbrev_zoo = |influences = |influenced = |prizes = |religion = |footnotes = |signature = }} '''John Jacob Abel''' ([[May 19]], [[1857]] – [[May 26]], [[1938]]) was a significant [[United States of America|American]] [[biochemistry|biochemist]] and [[pharmacology|pharmacologist]]. Born near [[Cleveland, Ohio|Cleveland]], [[Ohio]], he graduated with a Ph.D. 1883 from the [[University of Michigan]]. In [[1891]] he founded and chaired the first department of pharmacology in the United States at the University of Michigan. In [[1893]], he went on to chair the pharmacology department at [[Johns Hopkins University]]. In [[1897]], he was the second to isolate [[epinephrine]], also known as adrenaline (the first was [[Napoleon Cybulski]] in 1895), although the extracts he produced have been shown to be mostly an inactive metabolite and the first pure extracts were produced by the Japanese [[Jokichi Takamine]] (1854-1922) who patented the formulation under the name '''adrenalin'''. He later formulated the idea of the artificial [[kidney]] and in [[1914]] he isolated [[amino acids]] from the [[blood]]. He spent years unsuccessfully searching for the [[pituitary]] hormone, unaware that he was in fact looking for several hormones. In [[1926]], he reported the isolation and [[crystallization]] of [[insulin]], though this announcement was met with considerable scepticism and not generally accepted for many years. Abel also co-founded the ''[[Journal of Biological Chemistry]]'' with [[Christian Archibald Herter (physician)|Christian Archibald Herter]] in [[1905]] and the ''Journal of Pharmacology and Experimental Therapeutics'' in [[1909]]. ==References== *{{Citation |id = [[PMID]]:3517604 |url= http://www.ncbi.nlm.nih.gov/pubmed/3517604 |last=Gastel |first=B |publication-date= |year= |title=Abel and onward: some early history of hemodialysis. |volume=20 |issue=2 |periodical=Medical instrumentation |pages=62-4 }} *{{Citation |id = [[PMID]]:11615884 |url= http://www.ncbi.nlm.nih.gov/pubmed/11615884 |last=Becker |first=R A |publication-date=1982 |year=[[1982]] |title=The John Jacob Abel papers--primary sources for the history of American pharmacology. |volume=24 |issue=3 |periodical=Pharmacy in history |pages=115-6 }} *{{Citation |id = [[PMID]]:6760940 |url= http://www.ncbi.nlm.nih.gov/pubmed/6760940 |last=Parascandola |first=J |publication-date=1982 |year=[[1982]] |title=John J. Abel and the early development of pharmacology at the Johns Hopkins University. |volume=56 |issue=4 |periodical=Bulletin of the history of medicine |pages=512-27 }} *{{Citation |id = [[PMID]]:801548 |url= http://www.ncbi.nlm.nih.gov/pubmed/801548 |last=Harvey |first=A M |publication-date=1976 |year=[[1976]] |title=Pharmacology's giant: John Jacob Abel. |volume= |issue= |periodical=Johns Hopkins Med. J. Suppl. |pages=49-59 }} *{{Citation |id = [[PMID]]:4606906 |url= http://www.ncbi.nlm.nih.gov/pubmed/4606906 |last=Harvey |first=A M |publication-date=1974 Oct |year=[[1974]] |title=Pharmacology's giant: John Jacob Abel. |volume=135 |issue=4 |periodical=The Johns Hopkins medical journal |pages=245-58 }} * Rosenberg, Charles. "Abel, John Jacob." in ''[[Dictionary of Scientific Biography]].'' (1970). New York: Charles Scribner's Sons. Vol. 1: p.9-12. *{{Citation |id = [[PMID]]:5340582 |url= http://www.ncbi.nlm.nih.gov/pubmed/5340582 |last=Murnaghan |first=J H |last2=Talalay |first2=P |publication-date=1967 |year=[[1967]] |title=John Jacob Abel and the crystallization of insulin. |volume=10 |issue=3 |periodical=Perspect. Biol. Med. |pages=334-80 }} *{{Citation |id = [[PMID]]:14118479 |url= http://www.ncbi.nlm.nih.gov/pubmed/14118479 |last=DARBY |first=T D |publication-date=1964 Feb |year=[[1964]] |title=ON TEACHING PHARMACOLOGY AND THERAPEUTICS IN OUR MEDICAL SCHOOLS. DELIBERATION UPON AND A REPHRASING OF AN ARTICLE BY JOHN J. ABEL. |volume=67 |issue= |periodical=Am. Heart J. |pages=145-9 }} *{{Citation |id = [[PMID]]:13979597 |url= http://www.ncbi.nlm.nih.gov/pubmed/13979597 |last=SWAIN |first=H H |last2=Geiling |first2=E M |last3=Heingartner |first3=A |publication-date= |year= |title=John Jacob ABEL at Michigan. The introduction of pharmacology into the medical curriculum. |volume=29 |issue= |periodical=Medical bulletin (Ann Arbor, Mich.) |pages=1-14 }} *{{Citation |id = [[PMID]]:13573011 |url= http://www.ncbi.nlm.nih.gov/pubmed/13573011 |last=MARSHALL |first=E K |publication-date= |year= |title=An exhibit at the centennial celebration of John Jacob Abel's birth. |volume=32 |issue=4 |periodical=Bulletin of the history of medicine |pages=356-65 }} *{{Citation |id = [[PMID]]:13489405 |url= http://www.ncbi.nlm.nih.gov/pubmed/13489405 |last=SOLLMAN |first=T |last2=AMBERG |first2=S |last3=VOEGTLIN |first3=C |last4=ROWNTREE |first4=L G |publication-date=1957 Dec |year=[[1957]] |title=Centenary of the birth of John Jacob Abel. |volume=101 |issue=6 |periodical=Bulletin of the Johns Hopkins Hospital |pages=298-328 }} {{DEFAULTSORT:Abel, John Jacob}} [[Category:American biochemists]] [[Category:American pharmacologists]] [[Category:1857 births]] [[Category:1938 deaths]] [[Category:Foreign Members of the Royal Society]] {{US-biochemist-stub}} [[cs:John Jacob Abel]] [[de:John Jacob Abel]] [[es:John Jacob Abel]] [[it:John Jacob Abel]] [[nl:John Jacob Abel]] [[pt:John Jacob Abel]] [[ro:John Jacob Abel]]