Koplik's spots
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2008-05-30T05:21:56Z
Pyrospirit
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Reverted edits by [[Special:Contributions/67.164.75.98|67.164.75.98]] ([[User talk:67.164.75.98|talk]]) to last version by 189.142.235.102
'''Koplik's spots''' (kop'liks) are small, irregular, red spots with a minute bluish white speck in the center of each seen on the [[cheek|buccal]] mucosa and [[tongue|lingual]] mucosa ([[mucous membrane]] of the inside of the cheek and tongue) and are [[pathognomonic]] of early stage [[measles]]. They are named after [[Henry Koplik]] (1858-1927), an [[United States|American]] [[pediatrician]] who first described them in [[1896]].
They often appear a few days before the rash arrives and can be a useful sign to look for in children known to be exposed to the [[measles virus]].
The first description of these spots by some authors are ascribed to Reubold, Würzburg 1854, by others to Johann Andreas Murray (1740-1791). Before Koplik, the German internist [[Carl Jakob Adolf Christian Gerhardt]] (1833-1902) in 1874, the Danish physician N. Flindt in 1879, and the Russian Nicolai Feodorowitsch von Filatov (1847-1902) in 1897, had observed equivalent phenomena.<ref name=Koplik>Koplik, H. The diagnosis of the invasion of measles from a study of the exanthema as it appears on the buccal mucous membrane. Archives of Pediatrics, New York, 1896; 13: 918-922." (accessed from http://www.whonamedit.com/synd.cfm/1437.html on 9/13/2006)</ref>
==References==
<references/>
==External links==
* [http://www.dentistry.leeds.ac.uk/oralpath/viruses/viral%20infections/340%20images/other%20viral%20images/koplik%27s%20spots.jpg Image of Koplik's spots] - dentistry.leeds.ac.uk.
[[es:Manchas de Koplik]]
[[pl:Plamki Koplika]]
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