Lev's disease 860894 220843478 2008-06-21T21:50:39Z DOI bot 6652755 Citation maintenance. You can [[WP:DOI|use this bot]] yourself! Please [[User:DOI_bot/bugs|report any bugs]]. {{Infobox_Disease | Name = {{PAGENAME}} | Image = | Caption = | DiseasesDB = 33970 | ICD10 = | ICD9 = {{ICD9|426.0}} | ICDO = | OMIM = 113900 | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = | }} '''Lev's disease''' (or '''Lenegre-Lev syndrome''') is an acquired [[complete heart block]] due to idiopathic fibrosis and calcification of the [[electrical conduction system of the heart|electrical conduction system]] of the [[heart]]. Lev's disease is most commonly seen in the elderly, and is often described as senile degeneration of the conduction system. One form has been associated with [[SCN5A]].<ref name="pmid10471492">{{cite journal |author=Schott JJ, Alshinawi C, Kyndt F, ''et al'' |title=Cardiac conduction defects associate with mutations in SCN5A |journal=Nat. Genet. |volume=23 |issue=1 |pages=20–1 |year=1999 |pmid=10471492 |doi=10.1038/12618}}</ref> ==History== It was described independently by two researchers in [[1964]],<ref>Lev M. ''Anatomic basis for atrioventricular block''. Am J Med 1964;37:742-8. PMID 14237429.</ref><ref>Lenegre J. ''Etiology and pathology of bilateral bundle branch block in relation to complete heart block.'' Prog Cardiovasc Dis 1964;6:409-444. PMID 14153648.</ref> but the condition is generally called after Lev. ==Associated conditions== [[Stokes-Adams attack]]s can be precipitated by this condition. These involve a temporary loss of consciousness due to ventricular fibrillation or asystole. ==References== <references/> ==See also== *[[Heart block]] {{disease-stub}} [[Category:Cardiac electrophysiology]] [[pl:Choroba Leva]]