Lymphangiogenesis
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2007-11-16T13:57:56Z
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Reverting possible vandalism by [[Special:Contributions/165.155.200.149]] to version by Jajws. If this is a mistake, [[User:ClueBot/FalsePositives|report it]]. Thanks, [[User:ClueBot|ClueBot]]. (73774) (Bot)
'''Lymphangiogesis''' is the formation of lymphatic vessels from pre-existing lymphatic vessels, in a method believed to be similar to [[blood vessel development]] or [[angiogenesis]].
Lymphangiogenesis plays an important [[physiological]] role in [[homeostasis]], [[metabolism]] and [[immunity (medical)|immunity]]. Lymphatic vessel formation has also been implicated in a number of pathological conditions including [[neoplasm]] [[metastasis]], [[oedema]], [[rheumatoid arthritis]],[[psoriasis]] and impaired wound healing.
The role of the [[lymphatic system]] in these diseases has received renewed interest largely due to the recent discovery of specific lymphatic markers such as [[Podoplanin]], [[LYVE-1]], [[PROX-1]], [[desmoplakin]], [[Vascular endothelial growth factor|VEGF-C]], [[VEGF-D]] and their receptor [[VEGFR-3]]. These specific markers have enabled new insights into functional and molecular [[lymphatic biology]].
== Useful resources ==
Lymphangiogenesis and disease
*Tumor-induced lymphangiogenesis: [http://www.nature.com/nm/journal/v7/n2/full/nm0201_151.html]
*Lymphangiogenesis and prosthetic joint failure: [http://www3.interscience.wiley.com/cgi-bin/fulltext/112222889/HTMLSTART]
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[[Category:Lymphatic system]]