Müllerian duct 776862 216401308 2008-06-01T13:57:22Z Thijs!bot 1392310 robot Adding: [[pl:Przewody Müllera]] {{Infobox Embryology | Name = {{PAGENAME}} | Latin = d. paramesonephricus | GraySubject = 252 | GrayPage = 1206 | Image = Gray1109.png | Caption = [[Urogenital sinus]] of female human [[embryo]] of eight and a half to nine weeks old. | Image2 = Gray993.png | Caption2 = Tail end of human embryo, from eight and a half to nine weeks old. | System = | CarnegieStage = 17 | Precursor = [[Intermediate mesoderm]] | GivesRiseTo = | MeshName = Mullerian+Ducts | MeshNumber = A16.254.570 | DorlandsPre = d_29 | DorlandsSuf = 12315002 | }} The '''Müllerian ducts''' (or '''paramesonephric ducts''') are paired ducts of the [[embryo]] which run down the lateral sides of the [[urogenital ridge]] and terminate at the [[mullerian tubercle| mullerian eminence]] in the primitive urogenital sinus. In the female, it will develop to form the fallopian tubes, uterus, and the upper portion of the vagina. It is tissue of [[mesoderm|mesodermal ]] origin. ==Development== [[Image:Gray1110.png|thumb|left|200px|Müllerian duct (blue) develops in females (middle image) and degenerates in males (bottom).]] Müllerian duct develops in females and degenerates in males. ==Regulation of development== The development of the Müllerian ducts is controlled by the presence or absence of "AMH", or [[Anti-müllerian hormone]] (also known as "MIF" for "Müllerian inhibiting factor", or "MIH" for "Müllerian inhibiting hormone"). {| class="wikitable" | male embryogenesis || The [[testes]] produce AMH and as a result the development of the Müllerian ducts is inhibited. || Disturbances can lead to [[persistent müllerian duct syndrome]]. || The ducts disappear except for the vestigial [[vagina masculina]] and the [[appendix testis]]. |- | female embryogenesis || The absence of AMH results in the development of female reproductive organs, as noted above. || Disturbance in the development may result in uterine absence ([[Mullerian agenesis]]) or [[uterine malformation]]s. || The ducts develop into the upper [[vagina]], [[cervix]], [[uterus]] and [[oviducts]]. |} ==Eponym== They are named after [[Johannes Peter Müller]], a [[physiologist]] who described these ducts in his text "Bildungsgeschichte der Genitalien" in [[1830]]. ==Additional images== <gallery> Image:Gray1107.png|Enlarged view from the front of the left Wolffian body before the establishment of the distinction of sex. Image:Gray1111.png|Transverse section of human embryo eight and a half to nine weeks old. </gallery> == See also == * [[Defeminization]] * [[prostatic utricle]] * [[List of homologues of the human reproductive system]] * [[Sexual differentiation]] * [[Wolffian duct]] ==External links== * {{EmbryologyUNC|genital|010}} {{Development of urinary and reproductive systems}} [[Category:Embryology|Muellerian duct]] [[Category:Developmental biology|Muellerian duct]] [[pl:Przewody Müllera]] [[ru:Мюллеров проток]]