Macroglossia
1965394
216645873
2008-06-02T16:03:01Z
AnjaManix
5964318
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = |
Caption = |
DiseasesDB = 7689 |
ICD10 = {{ICD10|Q|38|2|q|38}} |
ICD9 = {{ICD9|529.8}} |
ICDO = |
OMIM = 153630 |
MedlinePlus = |
eMedicineSubj = ent |
eMedicineTopic = 746 |
MeshID = D008260 |
}}
'''Macroglossia''' is the medical term for unusual enlargement ([[Organ hypertrophy|hypertrophy]]) of the [[tongue]]. Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping.
Macroglossia is common in primary and myeloma-related [[amyloidosis]]. Amyloidosis is an accumulation of insoluble proteins in tissues that impedes normal function. (Merck Manual 17th Ed.) Macroglossia is also a clinical feature in [[congenital hypothyroidism]], rare genetic syndromes such as [[Beckwith-Wiedemann syndrome]] and [[immunodeficiency, centromere instability and facial anomalies syndrome]], [[acromegaly]] and [[Hurler syndrome]].
==External links==
*[http://www.bcm.edu/oto/grand/52892.html Grand Rounds Site]
{{med-sign-stub}}
{{Congenital malformations and deformations of digestive system}}
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