Maud Menten 506933 225077890 2008-07-11T19:45:03Z DragonflySixtyseven 62058 trim [[Image:mlmenten.jpg|right|thumb|Maud Leonora Menten]] '''Maud Leonora Menten''' ([[March 20]], [[1879]] &ndash; [[July 26]], [[1960]]) was a [[Canada|Canadian]] medical scientist who made significant contributions to [[enzyme kinetics]] and [[histochemistry]]. Her name is associated with the famous [[Michaelis-Menten kinetics|Michaelis-Menten equation]]. Maud Menten was born in [[Port Lambton, Ontario]] and studied [[medicine]] at the [[University of Toronto]] (B.A. [[1904]], M.B. [[1907]], M.D. [[1911]]). She was among the first women in Canada to earn a medical doctorate. She completed her thesis work at [[University of Chicago]]. At that time women were not allowed to do research in Canada, therefore she decided to do research in other countries such as the [[United States]] and [[Germany]]. In [[1912]] she moved to [[Berlin]] where she worked with [[Leonor Michaelis]], obtaining a Ph.D. in [[1916]]. Menten worked as a pathologist at the [[University of Pittsburgh]] ([[1923]]&ndash;[[1950]]) and as a research fellow at the British Columbia Medical Research Institute ([[1951]]&ndash;[[1953]]). Her most famous work was on enzyme kinetics together with Michaelis, based on earlier findings of [[Victor Henri]]. This resulted in the [[Michaelis-Menten kinetics|Michaelis-Menten]] equations. Menten also invented the azo-dye coupling reaction for [[alkaline phosphatase]], which is still used in histochemistry. She characterised bacterial toxins from ''B. paratyphosus'', ''S. scarlatinae'' and ''[[Salmonella]] ssp.'') and conducted the first [[electrophoresis|electrophoretic]] separation of proteins in [[1944]]. She worked on the properties of [[hemoglobin]], regulation of [[blood sugar]] level, and kidney function. Despite suffering from arthritis she was also an accomplished musician and painter<ref>[http://jchemed.chem.wisc.edu/JCEWWW/Features/eChemists/document.php?chemid=2 JCE Online: Biographical Snapshots: Snapshot<!-- Bot generated title -->]</ref>; there were several exhibitions of her paintings. ==References== {{reflist}} {{DEFAULTSORT:Menten, Maud}} [[Category:1879 births]] [[Category:1960 deaths]] [[Category:Canadian expatriate academics in the United States]] [[Category:Canadian Medical Hall of Fame]] [[Category:Canadian medical researchers]] [[Category:People from Lambton County, Ontario]] [[Category:University of Pittsburgh faculty]] [[Category:Women chemists]] [[Category:Canadian chemists]] [[cs:Maud Leonora Menten]] [[de:Maud Menten]] [[es:Maude Menten]] [[fr:Maud Menten]] [[he:מוד מנטן]] [[ja:モード・メンテン]]