Megalocephaly 2412391 101559742 2007-01-18T14:29:21Z 155.37.215.212 not commonly seen in Down's Syndrome, but does occur in neurofibromatosis 1, Fragile X Syndrome, Sotos Syndrome, and Simpson-Golabi-Benel Syndrome In [[medicine]], '''megalocephaly''' is a [[birth defect]] that causes an abonormally large [[head]]. It is common in cases of [[retardation]] seen in neurofibromatosis 1, Fragile X Syndrome, Sotos Syndrome, and Simpson-Golabi-Benel Syndrome. Megalocephaly differs from [[hydrocephalus]] in that there is no increased intracranial pressure and the overgrowth is symmetrical. [[Category:Diseases]] {{disease-stub}}