Mitochondrial myopathy
2858614
210464648
2008-05-06T01:03:03Z
Rjwilmsi
203434
accessdate compliance to [[Template:Cite_web#Required_parameters|Template:Cite_web]], Replaced: accessdate = 8 February 2008 → accessdate = 2008-02-08 using [[Project:AutoWikiBrowser|AWB]]
{{Refimprove|date=February 2008}}
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = Diagram of an animal mitochondrion.svg |
Caption = Simplified structure of a typical mitochondrion |
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ICD10 = {{ICD10|G|71|3|g|70}} |
ICD9 = |
ICDO = |
OMIM = |
MedlinePlus = |
eMedicineSubj = |
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MeshID = D017240 |
}}
'''Mitochondrial myopathy''' are a type of [[myopathy]] associated with [[mitochondrial disease]].
==Treatment==
Although no cure currently exists, there is some hope for a treatment for this whole class of [[hereditary disease]]s with the use of an [[embryotic]] mitochindrial transplant. <ref Name="BBC_5_February_2008">{{cite web | title =Three-parent embryo formed in lab | work =Scientists believe they have made a potential breakthrough in the treatment of serious disease by creating a human embryo with three separate parents. | publisher = BBC News | date = Tuesday, 5 February 2008, 11:13 GMT | url =http://news.bbc.co.uk/2/hi/health/7227861.stm | format =web | doi = | accessdate = 2008-02-08 }}</ref>
==Examples==
Examples of Mitochondrial myopathy include:
* [[Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like syndrome]] (MELAS)
** varying degrees of cognitive impairment and dementia
** [[lactic acidosis]]
** [[stroke]]s
** [[transient ischemic attack]]s
** hearing loss
** [[dysmotility]]
** weight loss
* [[Myoclonic epilepsy and ragged-red fibers]] (MERRF)
** progressive myoclonic epilepsy
** clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "ragged-red fibers" when muscle is stained with modified Gomori trichrome stain
** short stature
* [[Kearns-Sayre syndrome]] (KSS)
** external [[ophthalmoplegia]]
** cardiac conduction defects
** sensory-neural hearing loss
* [[Progressive external ophthalmoplegia]] (PEO)
** progressive [[ophthalmoparesis]] is the cardinal feature
** symptomatic overlap with many other mitochondrial myopathies
==References==
{{reflist}}
{{PNS diseases of the nervous system}}
{{Mitochondrial diseases}}
[[Category:Muscular disorders]]
[[Category:Mitochondrial diseases]]