Neurofibroma 2966201 218855609 2008-06-12T13:37:06Z JAnDbot 1725149 robot Adding: [[cs:Neurinom]] {{Infobox_Disease | Name = {{PAGENAME}} | Image = Neurofibroma (1).jpg | Caption = Histopathologic image of cutanous neurofibroma obtained by biopsy | DiseasesDB = 23371 | ICD10 = | ICD9 = | ICDO = 9540-9550 | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D009455 | }} '''Neurofibroma''' is a type of [[nerve sheath tumor]]. In contrast to [[schwannomas]] -- another type of [[tumor]] arising from the [[Schwann cells]] -- neurofibromas incorporate all sorts of cells and structural elements in addition to the Schwann cells.<ref> Miller RT. Immunohistochemistry in the differential diagnosis of schwannoma and neurofibroma. Propath 2004 Oct. http://www.ihcworld.com/_newsletter/2004/2004-10_NF_vs_schwannoma_v1.pdf</ref> ==Presentation== Neurofibromas infiltrate the nerve and splay apart the individual nerve fibers. Although usually [[benign]], Neurofibromas can sometimes degenerate into [[cancer]]. Single neurofibromas often occur in middle and old age and grow at the margins of the peripheral nerves, displacing the nerve's main body. ==Treatment== [[Surgical]] resection is curative, although tumors are not easily removable if they surround important nerves such as the optic nerve. There is a risk of functional damage due to interference with the [[nerve]]. [[Debulking]] may be helpful.<ref name="pmid12828709">{{cite journal |author=Babovic S, Bite U, Karnes PS, Babovic-Vuksanovic D |title=Liposuction: a less invasive surgical method of debulking plexiform neurofibromas |journal=Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] |volume=29 |issue=7 |pages=785–7 |year=2003 |pmid=12828709 |doi=}}</ref> ==Notable Cases== In November 2006, an hour-long documentary was shown on the [[United Kingdom|British]] television network [[Channel 4]] about [[Facing the World]], an organization that helps children with severe facial disfigurements in developing countries. One of the children featured on the documentary was Arianto, an [[Indonesia|Indonesian]] boy who suffered from a severe form of neurofibroma resulting in hemifacial giganticism. ==See Also== [[Neurofibromatosis]] ==References== <references/> ==External links== * {{DermAtlas|67}} [[Category:Neurology]] [[Category:Types of cancer]] [[category:dermatology]] {{neuroscience-stub}} {{Nervous tissue tumors}} [[cs:Neurinom]] [[de:Schwannom]] [[pl:Nerwiakowłókniak]]