Neurofibroma
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2008-06-12T13:37:06Z
JAnDbot
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robot Adding: [[cs:Neurinom]]
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = Neurofibroma (1).jpg |
Caption = Histopathologic image of cutanous neurofibroma obtained by biopsy |
DiseasesDB = 23371 |
ICD10 = |
ICD9 = |
ICDO = 9540-9550 |
OMIM = |
MedlinePlus = |
eMedicineSubj = |
eMedicineTopic = |
MeshID = D009455 |
}}
'''Neurofibroma''' is a type of [[nerve sheath tumor]]. In contrast to [[schwannomas]] -- another type of [[tumor]] arising from the [[Schwann cells]] -- neurofibromas incorporate all sorts of cells and structural elements in addition to the Schwann cells.<ref> Miller RT. Immunohistochemistry in the differential diagnosis of schwannoma and neurofibroma. Propath 2004 Oct. http://www.ihcworld.com/_newsletter/2004/2004-10_NF_vs_schwannoma_v1.pdf</ref>
==Presentation==
Neurofibromas infiltrate the nerve and splay apart the individual nerve fibers. Although usually [[benign]], Neurofibromas can sometimes degenerate into [[cancer]].
Single neurofibromas often occur in middle and old age and grow at the margins of the peripheral nerves, displacing the nerve's main body.
==Treatment==
[[Surgical]] resection is curative, although tumors are not easily removable if they surround important nerves such as the optic nerve. There is a risk of functional damage due to interference with the [[nerve]]. [[Debulking]] may be helpful.<ref name="pmid12828709">{{cite journal |author=Babovic S, Bite U, Karnes PS, Babovic-Vuksanovic D |title=Liposuction: a less invasive surgical method of debulking plexiform neurofibromas |journal=Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] |volume=29 |issue=7 |pages=785–7 |year=2003 |pmid=12828709 |doi=}}</ref>
==Notable Cases==
In November 2006, an hour-long documentary was shown on the [[United Kingdom|British]] television network [[Channel 4]] about [[Facing the World]], an organization that helps children with severe facial disfigurements in developing countries. One of the children featured on the documentary was Arianto, an [[Indonesia|Indonesian]] boy who suffered from a severe form of neurofibroma resulting in hemifacial giganticism.
==See Also==
[[Neurofibromatosis]]
==References==
<references/>
==External links==
* {{DermAtlas|67}}
[[Category:Neurology]]
[[Category:Types of cancer]]
[[category:dermatology]]
{{neuroscience-stub}}
{{Nervous tissue tumors}}
[[cs:Neurinom]]
[[de:Schwannom]]
[[pl:Nerwiakowłókniak]]