Osmolal gap 2641438 186045436 2008-01-22T04:29:56Z SkierRMH 2618808 clean up w/defaultsort , replaced: Category:Electrolyte disturbance → Category:Electrolyte disturbances using [[Project:AutoWikiBrowser|AWB]] '''Osmolal gap''' is the difference between measured [[serum osmolality]] and calculated serum osmolality. It is typically calculated as: OG = measured serum osmolality - (2 X serum [[sodium]] + [[blood sugar|serum glucose]]/18] + serum [[urea]]/2.8/]) Where: * 2 X serum sodium + serum glucose + serum urea = the calculated serum osmolality and all measures are in [[mmol/L]]. * OG = osmolal gap In US customary units the calculated osmolarity is: ( 2 x sodium ) + glucose/18 + BUN/2.8. A normal osmolal gap is < 12 mmol/L. Causes of an elevated osmolal gap are numerous. Noted causes are: *[[ethanol]] intoxication *[[methanol]] ingestion *[[ethylene glycol]] ingestion ==See also== *[[Osmolality]] *[[Metabolic acidosis]] ==External links== *[http://www.fpnotebook.com/REN79.htm Osmolar gap] - fpnotebook.com *[http://www.fpnotebook.com/REN78.htm Serum Osmolality] - fpnotebook.com *[http://www.anaesthesiamcq.com/AcidBaseBook/ab3_5.php Acid-Base Physiology] [[Category:Electrolyte disturbances]] [[Category:Nephrology]]