Oxybuprocaine
3750357
170775522
2007-11-11T17:03:05Z
Mfranck
258650
removed [[Category:Anesthesia]]
{{unreferenced|date=November 2006}}
{{drugbox
| IUPAC_name = 2-diethylaminoethyl 4-amino-3-butoxy-benzoate
| image = Oxybuprocaine.svg
| CAS_number = 99-43-4
| ATC_prefix = D04
| ATC_suffix = AB03
| ATC_supplemental = {{ATC|S01|HA02}}
| PubChem = 4633
| DrugBank = APRD00817
| C = 17 | H = 29 | Cl = 1 | N = 2 | O = 3
| molecular_weight = 344.877 g/mol
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| pregnancy_category =
| legal_status =
| routes_of_administration =
}}
'''Oxybuprocaine''' is the name of a [[local anesthetic]], which is used especially in [[ophthalmology]] and [[otolaryngology]]. Oxybuprocaine is sold by [[Novartis]] under the brand names '''Novesine''' or '''Novesin'''.
== Where oxybuprocaine is used specifically ==
* In [[ophthalmology]] in order to numb the surface of the [[eye]] (the outermost layers of the [[cornea]] and [[conjunctiva]]) for the following purposes:
** In order to perform a [[tonometry|contact/applanation tonometry]].
** In order to remove small foreign objects from the uppermost layer of the cornea or conjunctiva.
* In [[otolaryngology]] for numbing the [[mucous membrane]]s of the [[nostrils]].
== Topical anesthetics in general ==
Oxybuprocaine like any other topical anesthetic used in the eye (like for example [[tetracaine]], [[proxymetacaine]] and [[proparacaine]]) can cause irreversible corneal damage and even complete destruction of the cornea when used excessively (excessive use means several times a day during several days or even weeks).
==See also==
*[[Topical anesthetic]]
{{Antipruritics}}
[[Category:Eye stubs]]
[[Category:Otolaryngology]]
[[Category:Local anesthetics]]
[[de:Oxybuprocain]]