Oxybuprocaine 3750357 170775522 2007-11-11T17:03:05Z Mfranck 258650 removed [[Category:Anesthesia]] {{unreferenced|date=November 2006}} {{drugbox | IUPAC_name = 2-diethylaminoethyl 4-amino-3-butoxy-benzoate | image = Oxybuprocaine.svg | CAS_number = 99-43-4 | ATC_prefix = D04 | ATC_suffix = AB03 | ATC_supplemental = {{ATC|S01|HA02}} | PubChem = 4633 | DrugBank = APRD00817 | C = 17 | H = 29 | Cl = 1 | N = 2 | O = 3 | molecular_weight = 344.877 g/mol | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | pregnancy_category = | legal_status = | routes_of_administration = }} '''Oxybuprocaine''' is the name of a [[local anesthetic]], which is used especially in [[ophthalmology]] and [[otolaryngology]]. Oxybuprocaine is sold by [[Novartis]] under the brand names '''Novesine''' or '''Novesin'''. == Where oxybuprocaine is used specifically == * In [[ophthalmology]] in order to numb the surface of the [[eye]] (the outermost layers of the [[cornea]] and [[conjunctiva]]) for the following purposes: ** In order to perform a [[tonometry|contact/applanation tonometry]]. ** In order to remove small foreign objects from the uppermost layer of the cornea or conjunctiva. * In [[otolaryngology]] for numbing the [[mucous membrane]]s of the [[nostrils]]. == Topical anesthetics in general == Oxybuprocaine like any other topical anesthetic used in the eye (like for example [[tetracaine]], [[proxymetacaine]] and [[proparacaine]]) can cause irreversible corneal damage and even complete destruction of the cornea when used excessively (excessive use means several times a day during several days or even weeks). ==See also== *[[Topical anesthetic]] {{Antipruritics}} [[Category:Eye stubs]] [[Category:Otolaryngology]] [[Category:Local anesthetics]] [[de:Oxybuprocain]]