Perilymph
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2008-05-27T20:10:29Z
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[[Image:Cochlea-crosssection.png|thumb|300px|Cross-section of [[cochlea]]. Perilymph is located in the [[scala tympani]] and [[scala vestibuli]] - the aqua regions at the top and bottom of the diagram.]]
'''Perilymph''' is an extracellular fluid located within the [[cochlea]] (part of the [[ear]]) in 2 of its 3 compartments; the [[scala tympani]] and [[scala vestibuli]]. The ionic composition of perilymph is comparable to that of [[Blood plasma|plasma]] and [[cerebrospinal fluid]]. The major cation of [[perilymph]] is [[sodium]].
==Perilymph vs. endolymph==
The third compartment of the ear, the [[cochlear duct]] (or scala media) contains [[endolymph]]. Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph.<ref>{{cite journal |author=Konishi T, Hamrick PE, Walsh PJ |title=Ion transport in guinea pig cochlea. I. Potassium and sodium transport |journal=Acta Otolaryngol. |volume=86 |issue=1-2 |pages=22–34 |year=1978 |pmid=696294 |doi=}}</ref>
==Clinical significance==
It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in [[Meniere's disease]].
==External links==
* http://oto.wustl.edu/cochlea/intro3.htm
==References==
<references/>
{{Anatomy-stub}}
{{Auditory and vestibular systems}}
[[Category:Ear]]
[[de:Perilymphe]]
[[id:Perilimfe]]
[[pl:Przychłonka]]
[[pt:Perilinfa]]