Perilymph 2734348 215345760 2008-05-27T20:10:29Z DOI bot 6652755 Citation maintenance. You can [[WP:DOI|use this bot]] yourself! Please [[User:DOI_bot/bugs|report any bugs]]. {{expert}} [[Image:Cochlea-crosssection.png|thumb|300px|Cross-section of [[cochlea]]. Perilymph is located in the [[scala tympani]] and [[scala vestibuli]] - the aqua regions at the top and bottom of the diagram.]] '''Perilymph''' is an extracellular fluid located within the [[cochlea]] (part of the [[ear]]) in 2 of its 3 compartments; the [[scala tympani]] and [[scala vestibuli]]. The ionic composition of perilymph is comparable to that of [[Blood plasma|plasma]] and [[cerebrospinal fluid]]. The major cation of [[perilymph]] is [[sodium]]. ==Perilymph vs. endolymph== The third compartment of the ear, the [[cochlear duct]] (or scala media) contains [[endolymph]]. Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells. The electric potential of endolymph is ~80-90 mV more positive than perilymph.<ref>{{cite journal |author=Konishi T, Hamrick PE, Walsh PJ |title=Ion transport in guinea pig cochlea. I. Potassium and sodium transport |journal=Acta Otolaryngol. |volume=86 |issue=1-2 |pages=22–34 |year=1978 |pmid=696294 |doi=}}</ref> ==Clinical significance== It has also been suggested that perilymph and endolymph participate in a unidirectional flow that is interrupted in [[Meniere's disease]]. ==External links== * http://oto.wustl.edu/cochlea/intro3.htm ==References== <references/> {{Anatomy-stub}} {{Auditory and vestibular systems}} [[Category:Ear]] [[de:Perilymphe]] [[id:Perilimfe]] [[pl:Przychłonka]] [[pt:Perilinfa]]