Phosphorolysis
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160658440
2007-09-27T09:19:50Z
Malcolma
320496
cat
{{Orphan|date=November 2006}}
'''Phosphorolysis''' is the [[cleavage]] of a compound in which inorganic [[phosphate]] is the attacking group. It is analogous to [[hydrolysis]].
An example of this is glycogen breakdown by glycogen phosphorylase, which catalyzes attack by inorganic phosphate on the terminal glycosyl residue at the nonreducing end of a glycogen molecule. The result is Glucose 1-phosphate and Glycogen (or starch) (n-1) glucose units.
In addition, sometimes phosphorolysis is preferable to hydrolysis (like in the breakdown of glycogen or starch, as in the example above) because glucose 1-phosphate yields more ATP than does free glucose when subsequently catabolized to pyruvate.
Another example of phosphorolysis is seen in the conversion of Glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate in glycolysis. The mechanism involves phosphorolysis.
{{reaction-stub}}
[[Category:Chemical processes]]