Pouchitis
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2007-11-12T01:26:43Z
Pearrari
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'''Pouchitis''' is inflammation of the [[ileo-anal pouch|ileal pouch]], which is created in the management of patients with [[ulcerative colitis]], [[indeterminate colitis]], or, rarely, other [[colitis|colitides]].<ref>[http://www.mayoclinic.org/pouchitis/ Mayo Clinic on Pouchitis]</ref><ref>[http://usagiedu.com/articles/pouch/pouch.pdf Univ. of Alabama article]</ref>
Patients with pouchitis typically present with bloody [[diarrhea]], urgency in passing stools, or discomfort while passing stools. Rarely, pain can occur with pouchitis.
[[Endoscopy]] in patients with pouchitis usually reveals erythematous pouch [[mucosa]], loss of pseudocolonic vaculature or other architecture, and friability of the mucosa. Biopsies show evidence of inflammatory cells or [[red blood cells]] in the [[lamina propria]].
Pouchitis is usually treated with antibiotics, and specifically usually with [[ciprofloxacin]] and [[metronidazole]]. In refractory cases, probiotics such as [[VSL-3]] and Bio-K+ may be useful.<ref>[http://www.mayoclinic.org/pouchitis/treatment.html Mayo on Pouchitis Treatment]</ref>
== References ==
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[[Category:gastroenterology]]
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