Povidone-iodine 1817669 221107248 2008-06-23T02:14:53Z DIO 7236208 {{drugbox | IUPAC_name = 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine. | image = | CAS_number = 25655-41-8 | ATC_prefix = S01 | ATC_suffix = AX18 | ATC_supplemental = {{ATC|D08|AG02}} {{ATC|D09|AA09}} {{ATC|D11|AC06}} {{ATC|G01|AX11}} {{ATC|R02|AA15}} | PubChem = | DrugBank = | chemical_formula = (C<sub>6</sub>H<sub>9</sub>NO)<sub>n</sub>·xI | molecular_weight = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_US = <!-- A / B / C / D / X --> | pregnancy_category= | legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --> | legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --> | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_status = | routes_of_administration = topical, when formulated }} '''Povidone-iodine''' ('''PVPI''') is a water-[[soluble]] [[complex (chemistry)|complex]] of [[iodine]] with [[poly vinyl pyrrolidone|polyvinylpyrrolidone]] (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis<ref>[http://www.usp.org/USPNF/faq.html#III_Q3 United States Pharmacopeia]</ref>. PVPI can be further formulated into topical antiseptic products as a solution (with [[surfactants]] and/or [[alcohol]]), [[aerosol]] or [[ointment]] at concentrations from 7.5% to 10%. These products are sold [[over-the-counter drug|over-the-counter (OTC)]] and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine. It works through disruption of pathogen cell walls. ==Notes and references== <div class="references-small"> <references/> </div> ==See also== * [[Tincture of iodine]] * [[Lugol's iodine]] * [[Betadine]] {{antimicrobial-stub}} {{Antiseptics and disinfectants}} {{Medicated dressings}} {{Other dermatological preparations}} {{Gynecological anti-infectives and antiseptics}} {{Throat preparations}} [[Category:Antiseptics]] [[Category:Iodine]] [[de:Povidon-Iod]] [[es:Povidona yodada]] [[nl:Povidonjodium]] [[ja:ポビドンヨード]] [[pt:Iodopovidona]] [[ru:Повидон-йод]]