Povidone-iodine
1817669
221107248
2008-06-23T02:14:53Z
DIO
7236208
{{drugbox
| IUPAC_name = 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine.
| image =
| CAS_number = 25655-41-8
| ATC_prefix = S01
| ATC_suffix = AX18
| ATC_supplemental = {{ATC|D08|AG02}} {{ATC|D09|AA09}} {{ATC|D11|AC06}} {{ATC|G01|AX11}} {{ATC|R02|AA15}}
| PubChem =
| DrugBank =
| chemical_formula = (C<sub>6</sub>H<sub>9</sub>NO)<sub>n</sub>·xI
| molecular_weight =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category=
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status =
| routes_of_administration = topical, when formulated
}}
'''Povidone-iodine''' ('''PVPI''') is a water-[[soluble]] [[complex (chemistry)|complex]] of [[iodine]] with [[poly vinyl pyrrolidone|polyvinylpyrrolidone]] (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis<ref>[http://www.usp.org/USPNF/faq.html#III_Q3 United States Pharmacopeia]</ref>.
PVPI can be further formulated into topical antiseptic products as a solution (with [[surfactants]] and/or [[alcohol]]), [[aerosol]] or [[ointment]] at concentrations from 7.5% to 10%. These products are sold [[over-the-counter drug|over-the-counter (OTC)]] and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine.
It works through disruption of pathogen cell walls.
==Notes and references==
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==See also==
* [[Tincture of iodine]]
* [[Lugol's iodine]]
* [[Betadine]]
{{antimicrobial-stub}}
{{Antiseptics and disinfectants}}
{{Medicated dressings}}
{{Other dermatological preparations}}
{{Gynecological anti-infectives and antiseptics}}
{{Throat preparations}}
[[Category:Antiseptics]]
[[Category:Iodine]]
[[de:Povidon-Iod]]
[[es:Povidona yodada]]
[[nl:Povidonjodium]]
[[ja:ポビドンヨード]]
[[pt:Iodopovidona]]
[[ru:Повидон-йод]]