Primary peritoneal cancer
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2008-05-23T13:05:36Z
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{{Infobox_Disease |
Name = {{PAGENAME}} |
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ICD10 = {{ICD10|C|48|1|c|45}}-{{ICD10|C|48|2|c|45}} |
ICD9 = {{ICD9|158}} |
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MeshID = D010534 |
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'''Primary peritoneal cancer''' or '''carcinoma''' ("PPCa")<ref name="pmid16515579">{{cite journal |author=Jaaback KS, Ludeman L, Clayton NL, Hirschowitz L |title=Primary peritoneal carcinoma in a UK cancer center: comparison with advanced ovarian carcinoma over a 5-year period |journal=Int. J. Gynecol. Cancer |volume=16 Suppl 1 |issue= |pages=123–8 |year=2006 |pmid=16515579 |doi=10.1111/j.1525-1438.2006.00474.x |url=http://dx.doi.org/10.1111/j.1525-1438.2006.00474.x}}</ref> is a [[cancer]] of the [[cell (biology)|cells]] lining the [[peritoneum]], or abdominal cavity.
Some studies indicate that 7–20% of initially diagnosed epithelial ovarian cancers could be properly reclassified as primary peritoneal cancers.
==Causes==
Although the precise causes are not known, an link with certain variants of [[BRCA]] has been described.<ref name="urlGynecologic Cancer Treatment – Primary Peritoneal Cancer - Dana-Farber Cancer Institute">{{cite web |url=http://www.dfci.harvard.edu/pat/adult/gynecologic-cancer/diseases-treated/primary-peritoneal-cancer.html |title=Gynecologic Cancer Treatment – Primary Peritoneal Cancer - Dana-Farber Cancer Institute |format= |work= |accessdate=}}</ref>
An association with [[vascular endothelial growth factor]] has been observed.<ref name="pmid18024863">{{cite journal |author=Burger RA, Sill MW, Monk BJ, Greer BE, Sorosky JI |title=Phase II trial of bevacizumab in persistent or recurrent epithelial ovarian cancer or primary peritoneal cancer: a Gynecologic Oncology Group Study |journal=J. Clin. Oncol. |volume=25 |issue=33 |pages=5165–71 |year=2007 |month=November |pmid=18024863 |doi=10.1200/JCO.2007.11.5345 |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=18024863}}</ref>
==Prognosis and treatment==
Prognosis and treatment is the same as for the most common variation of [[ovarian cancer]], which is [[epithelial]] ovarian cancer.<ref name="urlNew Drug Combination for Ovarian and Primary Peritoneal Cancers - National Cancer Institute">{{cite web |url=http://www.cancer.gov/clinicaltrials/ft-MAYO-MC0261 |title=New Drug Combination for Ovarian and Primary Peritoneal Cancers - National Cancer Institute |format= |work= |accessdate=}}</ref><ref name="urleMedicine - Peritoneal Cancer : Article by Wissam Bleibel">{{cite web |url=http://www.emedicine.com/med/TOPIC1795.HTM |title=eMedicine - Peritoneal Cancer : Article by Wissam Bleibel |format= |work= |accessdate=}}</ref>
Elevated albumin levels have been associated with a more favorable prognosis.<ref name="pmid16876237">{{cite journal |author=Alphs HH, Zahurak ML, Bristow RE, Díaz-Montes TP |title=Predictors of surgical outcome and survival among elderly women diagnosed with ovarian and primary peritoneal cancer |journal=Gynecol. Oncol. |volume=103 |issue=3 |pages=1048–53 |year=2006 |month=December |pmid=16876237 |doi=10.1016/j.ygyno.2006.06.019 |url=http://linkinghub.elsevier.com/retrieve/pii/S0090-8258(06)00505-1}}</ref>
==Mesothelioma==
The cancer does involve [[mesothelial]] cells and can be medically described as [[mesothelioma]]; however, this cancer should '''not''' be confused with [[asbestos]]-related mesothelioma, which requires different treatments and has a much higher mortality rate.
==References==
{{reflist|2}}
== External links ==
* [http://www.cancerhelp.org.uk/help/default.asp?page=6029 Description] at [[National Health Service (England)]]
* [http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_ovarian_cancer_33.asp?rnav=cri Description] at [[American Cancer Society]]
* to view Leah Dorfman's battle with Peritoneal Cancer visit...<br>http://home.att.net/~leahland/peritonealcancer.html
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[[Category:Types of cancer]]
[[Category:Oncology]]
[[nl:Buikvlieskanker]]