Purinergic receptor 5665456 219488975 2008-06-15T13:51:19Z Alaibot 1324179 Robot: sorting stub (based on existing categorisation) '''Purinergic receptors''' are a family of newly characterized [[plasma membrane]] molecules involved in several and as yet only partially known cellular functions such as vascular reactivity, [[apoptosis]] and [[cytokine]] secretion. Little is known about the effect extracellular microenvironment has on their function. [[Fibroblasts]] share several features with [[smooth muscle]] cells and are an important constituent of the [[atherosclerotic]] plaque. This receptors have their effect of high [[glucose]] concentration on [[Adenosine triphosphate|ATP]]-mediated responses in human fibroblasts. The members of the family include the following: {| class="wikitable" | '''Name''' || '''Activation''' || '''Class''' |- | [[P1 receptors]] || [[adenosine]] || [[G protein-coupled receptor|G protein-coupled receptors]] |- | [[P2Y receptors]] || [[nucleotide]]s *[[Adenosine triphosphate|ATP]] *[[Adenosine diphosphate|ADP]] *[[Uridine triphosphate|UTP]] *[[Uridine diphosphate|UDP]] *[[UDP-glucose]] || [[G protein-coupled receptor|G protein-coupled receptors]] |- | [[P2X receptors]] || [[adenosine triphosphate|ATP]] || [[ligand-gated ion channel]] |} ==External links== *[http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1273 IUPHAR GPCR Database - Adenosine receptors] *[http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1294 IUPHAR GPCR Database - P2Y receptors] * {{MeshName|Purinergic+Receptors}} [[Category:G protein coupled receptors]] [[zh:嘌呤受体]] {{transmembranereceptor-stub}} {{Transmembrane receptors}} {{Ligand-gated ion channels}} {{G protein-coupled receptors}}