Sodium periodate
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2008-07-09T04:48:47Z
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'''Sodium periodate''' can refer to two different chemical compounds which are essentially sodium salts of the two varieties of periodate ion. Sodium metaperiodate (often abbreviated as m-periodate) has the formula NaIO<sub>4</sub>. Sodium orthoperiodate (often abbreviated as o-periodate) has the formula Na<sub>5</sub>IO<sub>6</sub>. Both salts are useful in certain synthetic chemistries for the oxidative power of the periodate ion.
Density is 3,865 kg m<sup>-3</sup>. It is soluble in water. When heated, it decomposes to form sodium iodate (NaIO<sub>3</sub>) and oxygen. This [[decomposition]] reaction is catalyzed by the presence of manganese(IV) oxide.
Sodium periodate is used to oxidize [[cellulose]] and create a [[biocompatible]] and [[biodegradable]] [[compound]] that can be used as [[suture]], as a [[scaffold]] for [[tissue engineering]], or for [[drug delivery]].
Sodium periodate can be used in solution to open saccharide rings between [[diol|vicinal diols]] leaving two aldehyde groups. This process is often used in labeling saccharides with fluorescent molecules or other tags such as [[biotin]]. Because the process requires vicinal diols, periodate oxidation is often used to selectively label [[RNA]] ([[ribose]] has vicinal diols) instead of [[DNA]] as [[deoxyribose]] does not have vicinal diols.
[[Category:Periodates]]
[[Category:Sodium compounds]]
[[ja:過ヨウ素酸ナトリウム]]
[[pl:Jodan(VII) sodu]]
[[zh:高碘酸钠]]