Stroma of cornea 5304212 194982106 2008-02-29T21:37:03Z KjellG 3798482 {{Infobox Anatomy | Name = {{PAGENAME}} | Latin = s. propria corneae | GraySubject = 225 | GrayPage = 1007 | Image = Gray871.png | Caption = Vertical section of human cornea from near the margin. (Waldeyer.) Magnified. <BR>1. [[Epithelium]]. <BR>2. [[Bowman's membrane|Anterior elastic lamina]]. <BR>3. [[substantia propria]]. <BR>4. [[Descemet's membrane|Posterior elastic lamina]]. <BR>5. [[Corneal endothelium|Endothelium]] of the [[anterior chamber]]. <BR>a. Oblique fibers in the anterior layer of the [[substantia propria]]. <BR>b. Lamellæ the fibers of which are cut across, producing a dotted appearance. <BR>c. [[Corneal]] corpuscles appearing [[fusiform]] in section. <BR>d. Lamellæ the fibers of which are cut longitudinally. <BR>e. Transition to the [[sclera]], with more distinct fibrillation, and surmounted by a thicker [[epithelium]]. <BR>f. Small blood vessels cut across near the margin of the [[cornea]]. | Image2 = | Caption2 = | System = | Precursor = | MeshName = | MeshNumber = | DorlandsPre = s_27 | DorlandsSuf = 12766936 | }} The '''substantia propria''' (or '''stroma of [[cornea]]''') is fibrous, tough, unyielding, and perfectly transparent. It is composed of about 200 flattened ''lamellæ'' (plates of collagen fibrils), superimposed one on another.<ref>Oyster, C. (1999) The Human Eye Structure and Function, Sinauer, §8</ref> These fibrils run at different angles between the [[Corneal limbus | limbi]]. Fibres of the layers frequently interweave, the anterior lamellæ interweaving more than posterior lamellæ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamellæ. The lamellæ are produced by [[keratocyte]]s, which occupy about 10% of the substantia propria. These lamellæ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the [[sclera]]. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients.{{Fact|date=June 2007}} [[Keratoconus]] is a condition caused by disorganised lamellæ, leading to a bulbous cornea. ==References== <references/> ==External links== * [http://www.opt.pacificu.edu/ce/catalog/10603-AS/Cornea.jpg Diagram at pacificu.edu] {{Eye}} [[Category:Eye]] [[no:Stroma i Cornea]] [[pl:Istota właściwa rogówki]]