Substantia nigra 46425 215153130 2008-05-26T23:04:01Z Boccobrock 218593 Revert addition of dubious unsourced content {{Infobox Brain| Name = Substantia nigra | Latin = | GraySubject = 188 | GrayPage = 802 | Image = cn3nucleus.png | Caption = Section through [[superior colliculus]] showing path of [[oculomotor nerve]]. | Image2 = Basal-ganglia-coronal-sections-large.png | Caption2 = [[Coronal plane|Coronal]] slices of human brain showing the [[basal ganglia]], [[globus pallidus]]: external segment (GPe), [[subthalamic nucleus]] (STN), [[globus pallidus]]: internal segment (GPi), and substantia nigra (SN, red). The right section is the deeper one, closer to the back of the head. | Width = 350 | IsPartOf = [[Mesencephalon|Midbrain]], [[Basal ganglia]]| Components = | Artery = | Vein = | BrainInfoType = hier | BrainInfoNumber = 527 | MeshName = Substantia+Nigra | MeshNumber = A08.186.211.132.659.687 | }} The '''substantia nigra''' ([[Latin]] for "black substance", [[Samuel Thomas von Sömmering|Sömmering]]) or '''locus niger''' is a heterogeneous portion of the [[Mesencephalon|midbrain]], separating the pes (foot) from the tegmentum (covering), and an accessory to the [[basal ganglia]] system. ==Components== It consists of two strongly contrasted ensembles, the ''[[pars compacta]]'' and adjacent dopaminergic groups, and another ensemble made up of the ''[[pars reticulata]]'' and the ''pars lateralis''. The latter two, along with the pallidal nuclei, are elements of the core of the [[basal ganglia]]. Although intricate and interconnected, the two ensembles must imperatively be distinguished. The ''substantia nigra compacta and surrounding'' is responsible for [[dopamine]] production in the brain, and therefore plays a vital role in [[reward system|reward]] and [[addiction]]. ==Additional images== <gallery> Image:Gray678.png|Schematic representation of the chief ganglionic categories (I to V). Image:Gray685.png|Deep dissection of brain-stem. Lateral view. Image:Gray690.png|Deep dissection of brain-stem. Ventral view. Image:Gray710.png|Coronal section through mid-brain. Image:Gray711.png|Transverse section of mid-brain at level of inferior colliculi. Image:Gray712.png|Transverse section of mid-brain at level of superior colliculi. Image:Gray717.png|Coronal section of brain immediately in front of pons. Image:Human brain frontal (coronal) section description 2.JPG|Human brain frontal (coronal) section Image:Dopamineseratonin.gif|Dopamine and serotonin </gallery> ==See also== *[[Basal ganglia]] *[[Brain stem]] *[[Cerebral peduncle]] *[[Dopamine]] *[[Mesencephalon]] *[[List of regions in the human brain]] *[[Parkinson's disease]] ==References== {{reflist}} ==External links== * {{BrainstemWisconsin|20Substantia}} * {{BrainMaps|substantia%20nigra|substantia nigra}} * [http://www.prometheus.uni-tuebingen.de/sec/vl/documents/42/bgana_normal.gif Diagram at uni-tuebingen.de] * [http://biomed.brown.edu/Courses/BI108/BI108_2003_Groups/Deep_Brain_Stimulation/motorloop.html Diagram and explanation of cortico-basal pathways] {{Mesencephalon}} {{Basal ganglia}} [[Category:Midbrain]] [[bg:Субстанция нигра]] [[da:Sorte substans]] [[de:Substantia nigra]] [[es:Sustancia negra]] [[fr:Substantia nigra]] [[it:Substantia nigra]] [[nl:Substantia nigra]] [[ja:黒質]] [[no:Substantia nigra]] [[pl:Istota czarna śródmózgowia]] [[pt:Substância negra]]