Superior colliculus
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2008-05-18T12:26:59Z
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Caption = Section through superior colliculus (unlabeled) showing path of oculomotor nerve |
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Caption2 = Scheme showing central connections of the [[optic nerve]]s and optic tracts. (Superior colliculus visible near center.) |
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The '''superior colliculus''' ([[Latin]], ''higher hill'') is a paired structure that is part of the [[brain]]'s [[tectum|tectal area]]. Superior Colliculus [[neurons]] respond to visual, auditory and [[somatosensory]] stimuli.<ref>University of California ''Primate Superior Colliculus'' http://keck.ucsf.edu/~sabes/Cortex/SC.htm</ref><ref>Wallace, M., et al (2005)''Multisensory Intergration in the Superior Colliculus of the Alert Cat'', Journal of Neurophysiology</ref>
==Structure and relations==
The two superior colliculi sit below the [[thalamus]] and surround the [[pineal gland]] in the [[mesencephalon]] of [[vertebrate]] brains. It comprises the [[caudal]] aspect of the [[midbrain]], posterior to the [[periaqueductal gray]] and immediately superior to the [[inferior colliculus]]. The inferior and superior colliculi are known collectively as the [[corpora quadrigemina]] (Latin, ''quadruplet bodies'').
==Function==
In [[human]]s, the superior colliculus (SC) is involved in the generation of [[saccade|saccadic]](fast) [[eye movements]] and eye-head coordination. [[Afferent nerve|Afferents]] to the SC originate in the [[cerebral cortex]], [[inferior colliculus]], [[retina]], [[basal ganglia]], and [[spinal cord]]. Efferents project to the [[paramedian pontine reticular formation]], [[spinal cord]], and elsewhere. In humans, as in most larger [[vertebrate]]s, sensory information that goes to the mesencephalon will be relayed via the [[thalamus]] to the cerebral cortex for interpretation. However, the SC can also mediate some [[oculomotor]] movements without cortical involvement.
The SC receives [[visual perception|visual]], as well as [[hearing (sense)|auditory]], inputs in its superficial layers, and the deeper layers of the colliculus are connected to many sensorimotor areas of the brain. The colliculus as a whole is thought to help orient the head and eyes toward something seen and heard. <ref>Eliana Klier, Hongying Wang & Douglas Crawford 'Three-Dimensional Eye-Head Coordination Is Implemented Downstream From the Superior Colliculus ', Journal of Neurophysiology v89 (2003) 2839-2853</ref><ref>Richard Krauzlis, Dorion Liston & Christopher Carello 'Target selection and the superior colliculus: goals, choices and hypotheses', Vision Research v44 (2004) 1445-1451</ref><ref>Alexander Kustov & David Robinson 'Shared neural control of attentional shifts and eye movements', Nature v384 (1996) 74-77</ref><ref>David Sparks 'Conceptual issues related to the role of the superior colliculus in the control of gaze', Current Opinion in Neurobiology v6 9 (1999) 698-707</ref>
[[Image:Gray719.png|thumb|300px|left|Hind- and mid-brains; postero-lateral view. Superior colliculus labeled in blue.]]
==Diversity==
===Primates===
It is usually accepted that the [[primate]] superior colliculus is unique among [[mammals]], in that it does not contain a complete map of the visual field seen by the contralateral eye. Instead, like the [[visual cortex]] and [[lateral geniculate nucleus]], each colliculus only represents the contralateral half of the [[visual field]], up to the midline, and excludes a representation of the ipsilateral half.<ref>Lane RH, Allman JM, Kaas JH, Miezin FM., 1973, The visuotopic organization of the superior colliculus of the owl monkey (Aotus trivirgatus) and the bush baby (Galago senegalensis). Brain Research 60(2):335-349.</ref> This functional characteristic is explained by the absence, in primates, of anatomical connections between the [[retinal ganglion cells]] in the temporal half of the [[retina]] and the contralateral superior colliculus. In other mammals, the retinal ganglion cells throughout the contralateral retina project to the contralateral colliculus. This distinction between primates and non-primates has been one of the key lines of evidence in support of the [[flying primates theory]] proposed by Australian neuroscientist [[Jack Pettigrew]] in 1986, after he discovered that flying foxes ([[megabat]]s) resemble primates in terms of the pattern of anatomical connections between the retina and superior colliculus. <ref>Pettigrew JD, 1986, Flying primates? Megabats have the advanced pathway from eye to midbrain. Science 231(4743):1304-1346.</ref>
===Other vertebrates===
In [[echolocating bat]]s, the SC has been shown to influence vocalization parameters and ear movements, both orienting components of the bat's [[biosonar]] system, thereby assisting in orienting movements.<ref>Doreen Valentine & Cynthia F. Moss 'Spatially selective auditory responses in the superior colliculus of the echolocating bat', Journal of Neuroscience v17 5 (1997) 1720-1733</ref>
The comparable area of the mesencephalon of non-mammalian vertebrates is called the '''optic tectum'''. In [[amphibians]], [[reptile]]s, and [[fish]], the optic tectum is the largest visual processing area, though its function remains largely unknown. It seems to be required for predator/prey discrimination leading to escape or hunting behavior respectively. In contrast, the role of the SC for visual discrimination is less prominent in more complex vertebrates.
In [[snake]]s with [[infrared vision]] like [[Pythonidae|python]]s and [[pit viper]]s though the initial neural input is through [[trigeminal nerve]] instead of [[optic nerve]], the rest of the processing circuits for this form of sense is quite similar to visual sense and thus involves the superior colliculi.
==See also==
*[[List of regions in the human brain]]
==Additional images==
<gallery>
Image:Gray682.png|Superficial dissection of brain-stem. Lateral view.
Image:Gray683.png|Dissection of brain-stem. Lateral view.
Image:Gray684.png|Deep dissection of brain-stem. Lateral view.
Image:Gray685.png|Deep dissection of brain-stem. Lateral view.
Image:Gray712.png|Transverse section of mid-brain at level of superior colliculi.
</gallery>
==External links==
* {{BrainstemWisconsin|23Colliculus}}
* {{BrainMaps|superior%20colliculus|superior colliculus}}
==References==
{{Reflist|2}}
{{Mesencephalon}}
[[Category:Brainstem]]
[[Category:Neuroanatomy]]
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[[el:Άνω Διδύμιο]]