Transposition of the great vessels
2062095
224618038
2008-07-09T18:00:18Z
Senaiboy
1637470
added See Also
{{Infobox_Disease |
Name = {{PAGENAME}} |
Image = |
Caption = |
DiseasesDB = 13259 |
ICD10 = {{ICD10|Q|20|3|q|20}} |
ICD9 = {{ICD9|745.1}} |
ICDO = |
OMIM = |
MedlinePlus = |
eMedicineSubj = ped |
eMedicineTopic = 2548 |
MeshID = D014188 |
}}
'''Transposition of the great vessels''' ('''TGV''') is a group of [[congenital]] [[congenital heart defect|heart defects]] ('''CHD'''s) involving an abnormal spatial arrangement of any of the primary [[blood vessel|blood vessels]]: [[superior vena cava|superior]] and/or [[inferior vena cava|inferior]] [[vena cavae]] ('''SVC''', '''IVC'''), [[pulmonary artery]], [[pulmonary vein]]s, and [[aorta]]. CHDs involving only the primary [[artery|arteries]] (pulmonary artery and aorta) belong to a sub-group called '''transposition of the great arteries''' ('''TGA''').
==History==
TGV was first described in [[1797]] by [[Matthew Baillie]].<ref>''The Morbid Anatomy of Some of the Most Important Parts of the Human Body'' (1793)</ref>
== Etiologies ==
D-TGA is often the result of a child born to a diabetic mother. Additionally, [[diabetic]] mothers are more likely to have [[aortic coarctation]] in their children.
==Description==
[[Image:normal heart.jpg|145px|thumb|right|Normal heart anatomy]]
In a normal [[heart]], [[oxygen]]-depleted [[blood]] is pumped from the right side of the heart, through the pulmonary artery, to the [[lung]]s where it is oxygenated. The oxygen-rich red blood then returns to the [[left heart]], via the [[pulmonary veins]], and is pumped through the aorta to the rest of the body, including the [[coronary circulation|heart muscle]] itself.
[[wiktionary:Transpose|Transpose]]d vessels can present a large variety of [[wiktionary:atriovenous|atriovenous]], [[wiktionary:ventriculoarterial|ventriculoarterial]] and/or [[wiktionary: arteriovenous|arteriovenous]] [[wiktionary:discordant|discordance]]. The effects may range from a change in [[blood pressure]] to an interruption in [[circulatory system|circulation]], depending on the nature and degree of the misplacement and which vessels are involved.
Although "transposed" literally means "swapped", many types of TGV involve vessels that are in abnormal positions, while not actually being swapped with each other. The terms TGV and TGA are most commonly used in reference to '''[[dextro-Transposition of the great arteries|dextro-TGA]]''' ('''d-TGA''') - in which the arteries ''are'' in swapped positions; however, both terms are also commonly used, though to a slightly lesser extent, in reference to '''[[Levo-Transposition of the great arteries|levo-TGA]]''' ('''l-TGA''') - in which both the arteries and the [[ventricle (heart)|ventricles]] are swapped; while other defects in this category are almost never referred to by either of these terms.
==Simple and complex TGV==
In many cases, TGV is accompanied by other heart defects, the most common type being [[wiktionary:intracardiac|intracardiac]] [[shunt (medical)|shunts]] such as [[atrial septal defect]] ('''ASD''') including [[patent foramen ovale]] ('''PFO'''), [[ventricular septal defect]] ('''VSD'''), and [[patent ductus arteriosus]] ('''PDA'''). [[Stenosis]], or other defects, of [[valve]]s and/or [[Blood vessel|vessels]] may also be present.
When no other heart defects are present it is called 'simple' TGV; when other defects are present it is called 'complex' TGV.
==See also==
*[[levo-Transposition of the great arteries]]
*[[dextro-Transposition of the great arteries]]
==References==
<references/>
==External links==
* [http://www.kumc.edu/instruction/medicine/pedcard/cardiology/pedcardio/dtgadiagram.gif Diagram at kumc.edu]
* [http://www.med.umich.edu/cvc/mchc/partran.htm Diagram and description at umich.edu]
{{Congenital malformations and deformations of circulatory system}}
[[Category:Congenital heart disease]]
[[de:Transposition der großen Arterien]]
[[es:Transposición de los grandes vasos]]
[[fr:Transposition des gros vaisseaux]]
[[nl:Transpositie van de grote vaten]]
[[nn:Transposisjon av dei store arteriane]]
[[zh:大血管轉位]]